Panic Disorder: Assessment, Management and Research Insights

Yong-Ku Kim (Editor)
Department of Psychiatry, Korea University Ansan Hospital, Gojan-Dong, Danwon-Gu, Kyunggido, Republic of Korea

Series: Psychology Research Progress
BISAC: PSY042000

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Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Although panic disorder may mimic medical conditions, patients with medical conditions that seem to pose a real life threat may be diagnosed when panic attacks, which are not well explained by any existing disease, repeatedly appear. After they accept the idea of possessing panic disorder, the most commonly asked question by patients is what has caused this condition. For the author, with more than 20 years of clinical experience, it is not easy to satisfy patients with simple answers. An exemplary explanation may be that the combination of heredity, environment, genetic-environmental interactions, neurotransmitters, the HPA axis, and any forms of stress affects the onset of panic disorder.

Genetic susceptibility obviously affects panic disorder, but does not account for up to 30-40% of occurrences. Stressful life events often precede the onset and seem to increase the risk of panic disorder development, but not in all cases. In fact, the cause of panic disorder is still unknown. However, step-by-step approaches toward understanding the causes and developing new treatments for panic disorder through research on the epidemiological studies, genetics, epigenetic studies, neuroimaging studies, and studies dissecting neural circuits for regulating normal fear and anxiety are being put into effect. The latest advances in therapy for treatment-resistant patients who do not respond well to therapy have been addressed in this book. This book is the result of a worldwide collaboration of experts who are outstanding in the research of panic disorder. The author hopes that this book will give patients, clinicians, and clinical researchers the latest insights into panic disorder. (Imprint: Nova)

Preface

Chapter 1. Fear Network in Panic Disorder: Evidence for Necessary Amendments (pp. 1-20)
Thomas Sobanski and Gerd Wagner

Chapter 2. Genetic, Epigenetic and Environmental Interaction in Panic Disorder (pp. 21-40)
Eun-Jeong Kim, Han-Joon Kim and Yong-Ku Kim

Chapter 3. Imaging Genetics in Panic Disorder (pp. 41-60)
Kang Soo Lee and Sang Hyuk Lee

Chapter 4. The Role of the Sympathetic Nervous System, Neuroinflammation and Alterations of the Brain in Panic Disorder (pp. 61-76)
Eunsoo Won and Yong-Ku Kim

Chapter 5. The Assessment and Treatment of Suicide in Panic Disorder (pp. 77-90)
Sunyoung Kim and Se-Won Lim

Chapter 6. Risk Factors and Preventions in Panic Disorder (pp. 91-108)
Cheolmin Shin, Kwang-Yeon Choi, and Yong-Ku Kim

Chapter 7. Panic Disorder Neuroimaging Focused on MRI (pp. 109-132)
Chien-Han Lai

Chapter 8. Alterations of the Hypothalamic-Pituitary-Adrenal Axis in Panic Disorder (pp. 133-150)
Gloria-Beatrice Wintermann

Chapter 9. Neurobiology and Neuroanatomy of Panic Disorder (pp. 151-168)
Michel Bourin

Chapter 10. Pharmacological and Non-Pharmacological Approaches for Treatment-Resistant Panic Disorder (pp. 169-194)
Rafael C. Freire, Morena M. Zugliani, Rafael F. Garcia and Antonio E. Nardi

Chapter 11. Psychotherapies of Panic Disorder (pp. 195-220)
Min-Kyu Song and Won Kim

Chapter 12. Internet-Based Cognitive Behavioral Therapy and Online Mindfulness Training for Panic Disorder (pp. 221-246)
Jennifer Apolinário-Hagen and Christel Salewski

Index (pp. 249)

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