Oxidative Stress: Causes, Role in Diseases and Biological Effects


Cassidy Croft (Editor)

Series: Cell Biology Research Progress
BISAC: SCI017000

Active oxygen species are produced as inescapable by-products of a normal aerobic metabolism, and their production is further enhanced by exposure to certain environmental conditions, or as a result of some diseases. Oxidative stress is defined as an imbalance between the production of free radicals (FR) and antioxidant defenses in favor of the former, which can result from an excess of prooxidant, antioxidant deficiency or both factors. There are many kinds of FR, but these can be grouped together under the name of reactive oxygen species (ROS) or reactive nitrogen species (RNS), determined by the ability of each species according to the four basic characteristics: reactivity, specificity, selectivity and diffusivity. This book aims to discuss the biological effects, role in diseases, and causes of oxidative stress. Some of the topics provided include oxidative stress in biofilms; age realtion to oxidative stress; controlling of oxidative stress in non-alcoholic steatohepatitis; and the role of nitric oxide toxicity and oxidative stress in graft vs. host disease. (Imprint: Nova Biomedical )


Table of Contents

Table of Contents


Chapter 1. Oxidative Stress and Mitochondrial Defect in Neuromuscular Disorders: Source or Symptoms?
Nanna Cornelius, Niels Gregersen, Zeynep Tümer and Rikke K. J. Olsen (Applied Human Molecular Genetics, Kennedy Center, Copenhagen University Hospital, Rigshospitalet, Glostrup, Denmark, and others)

Chapter 2. Oxidative Stress in Biofilms: Causes, Role in Diseases and Biological Effects
María Gabriela Paraje (IMBIV (CONICET) y Departamento de Farmacia, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Haya de la Torre y Medina Allende, Córdoba, Argentina)

Chapter 3. Oxidative Stress and Age Related Macular Degeneration
N. Manresa, Ph.D., J. Mulero, Ph.D., M. Losada and P. Zafrilla, Ph.D. (Department of Food Technology and Nutrition. Catholic University of San Antonio. Murcia, Spain, and others)

Chapter 4. Traditional Chinese Medicine Exerts Cardioprotective Effects Against Myocardial Ischemia/Reperfusion Injury
Ru Tie, Wenjuan Xing, Lele Ji and Haifeng Zhang (Experiment Teaching Center and Department of Physiology, Fourth Military Medical University, China)

Chapter 5. Controlling Oxidative Stress in Non-Alcoholic Steatohepatitis (NASH)
Akinobu Takaki, Daisuke Kawai and Kazuhide Yamamoto (Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan)

Chapter 6. Current Approaches to Redox Therapies in Multiple Sclerosis
Elżbieta Miller, Jarosław Jakubik and B. Wachowicz (Department of Physical Medicine, Medical University of Lodz, Poland, and others)

Chapter 7. The Role of Nitric Oxide Toxicity and Oxidative Stress in Graft vs. Host Disease
Osnat Almogi-Hazan, Reut Shainer, Eytan R. Barnea and Reuven Or (Department of Bone Marrow Transplantation, Hadassah-Hebrew University Medical Center, Jerusalem, Israel, and others)

Chapter 8. Review of the Oxidative Stress Role in the Pathophysiology of Different Hearing Disorders: New Insight in the Role of Oxidative Stress in the Pathophysiology of Otosclerosis
Milan Rudić, M.D., Ph.D. (ENT Department, General Hospital Zadar, Croatia)

Chapter 9. Oxidative Stress in Eales’ Disease: An Update
R. Saravanan and K. N. Sulochana (R.S. Mehta Jain Department of Biochemistry and Cell Biology, Vision Research Foundation, Sankara Nethralaya, Chennai, India)


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