Oxidative Stress and Antioxidant Defense: Biomedical Value in Health and Diseases

Md. Sahab Uddin (Editor)
Department of Pharmacy, Southeast University, Dhaka, Bangladesh

Aman B. Upaganlawar (Editor)
Department of Pharmacology, SNJB’s SSDJ College of Pharmacy, Maharashtra, India

Series: New Developments in Medical Research
BISAC: MED022090

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Volume 10

Issue 1

Volume 2

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Oxidative Stress and Antioxidant Defense: Biomedical Value in Health and Diseases represent current findings on the impact of oxidative stress in the pathogenesis of diseases and underlying mechanisms of antioxidants influencing health and disease processes.

This book is divided into seven sections that describe how antioxidants defend oxidative stress-mediated diseases as well as recent developments, future opportunities, and challenges. Sections 1 analyzes the role of oxidative stress in aging and associated diseases as well as the use of antioxidants in health maintenance, preventing and repairing injuries caused by oxidative stress. Section 2 represents the status of various antioxidants in cigarette smoking and antioxidant defense against exercise-induced oxidative stress.

Section 3 focuses on the effect of oxidative stress in the pathogenesis of neurodegeneration and the existing status of antioxidant therapy. Section 4 covers the impact of oxidative stress at different levels of chronic degenerative diseases, as well as treatment with antioxidants to revert and diminish the cellular injury. Section 5 offers the importance of antioxidants in abating the pathological processes involved in hypertension and stroke. Section 6 presents the complexity associated with oxidative stress and metabolic disorders as well as the potential of antioxidants used in amelioration of related pathologies. Section 7 discusses the antioxidant defense against oxidative stress-mediated erectile dysfunctions and the significance of antioxidants in pregnancy.

This book represents the copious set of specific research updates and diaphanous understanding of oxidative stress-mediated cellular damages and role of antioxidants in disease processes from experienced and eminent academicians, researchers, and scientists from throughout the world. This book is suitable for professionals, academicians, students, researchers, scientists and industrialists around the world in the biomedical, health, and life science fields.
(Imprint: Nova)

Dedication

Preface

Acknowledgements

Chapter 1. Aging, Oxidative Stress and Antioxidants
(Shalini Mani and Aarushi Singh, Jaypee Institute of Information Technology, Noida, India)

Chapter 2. Free Radicals and Antioxidants in Human Health and Diseases
(Meenakshi Kaira, Abhilasha Ahlawat, Vaibhav Walia and Munish Garg, Maharshi Dayanand University, Rohtak, India)

Chapter 3. Antioxidant Status and Cigarette Smoking
(Tanuj Joshi and Archana Negi Sah, Kumaun University, Nainital, India)

Chapter 4. Oxidants, Antioxidants in Physical Exercise
(Vaishali R. Undale, Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Maharashtra, India)

Chapter 5. Antioxidants Signaling in Neurodegenerative Disorders
(Abhilasha Ahlawat, Vaibhav Walia, Meenakshi Kaira and Munish Garg, Maharshi Dayanand University, Rohtak, India)

Chapter 6. Antioxidants against Stress-Induced Memory Dysfunction
(Chandrasekar S. B., Anil T. Pawar, Lokesh Prasad M. S. and Hemavathi G., Hi-Tech Lab, Drug Testing Laboratory, Drug Control Department, Bangalore, India, and others)

Chapter 7. Neuroprotective Strategies for Oxidative Stress-Mediated Alzheimer's Disease
(Manoj Govindarajulu, Sindhu Ramesh, Ayaka Fujihashi, Mansour Alturki, Tyler Lynd, Gayatri Devi Donepudi, Vishnu Suppiramaniam, Timothy Moore and Muralikrishnan Dhanasekaran, Auburn University, Alabama, US, and others)

Chapter 8. Oxidant/Antioxidant Imbalances in Huntington's Disease
(Arup Kumar Misra, Surjit Singh, Pramod Kumar Sharma, Sneha Ambwani and Sushil Kumar Varma, All India Institute of Medical Sciences, Jodhpur, India, and others)

Chapter 9. Oxidative Damage and Antioxidative Defense Mechanisms in Inflammation
(Newman Osafo, Joseph Owusu-Sarfo and David Darko Obiri, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana)

Chapter 10. Free Radicals and Antioxidant Defense in Asthma
(Rashmi Pandey, Priyanka Tiwari, Ved Prakash, Vivek Kumar Gupta and Bechan Sharma, King George Medical University, Lucknow, India, and others)

Chapter 11. Antioxidant Activity and Cancer
(Newman Osafo, Joseph Owusu-Sarfo, Eyitayo Adeyemi Oyindamola, Sophia Naa Ayikailey Ankrah and David Darko Obiri, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana, and others)

Chapter 12. Oxidants and Antioxidant Defense in HIV/AIDS
(Hrushikesh E. Velis, Amrutvahini College of Pharmacy, Sangamner, India)

Chapter 13. Antioxidants and Antihypertensive Potency
(Abdulla Sherikar, Aman Upaganlawar, Sameer Goyal and Chandrashekhar Upasani, SVKM’s Institute of Pharmacy, Maharashtra, India, and others)

Chapter 14. Radical Approaches to Stroke
(Vipin Dhote, Avinash Singh Mandloi, Durgesh Nandan Shukla, Priyanshi Kapoor and Aditya Ganeshpurkar, VNS Group of Institutions, Bhopal, India, and others)

Chapter 15. Free Radicals, Antioxidants and Diabetes
(Seetha Harilal and Rajesh K., Kerala University of Health Sciences, Kerala, India)

Chapter 16. Antioxidant Defense in Diabetic Nephropathy
(Manojkumar S. Mahajan, Vishal S. Gulecha, Aman Upaganlawar and Chandrashekhar D. Upasani, SNJB’s Shriman Sureshdada Jain College of Pharmacy, Nashik, India)

Chapter 17. Antioxidants in Glycation Related Diseases
(Ahmad Ali, Additiya Paramanya, Prairna, Koula Doukani and Sadaf Zehra, University of Mumbai, Mumbai, India, and others)

Chapter 18. Oxidative Stress and Antioxidant Therapy in Erectile Dysfunction
(Yogesh Chand Yadav, Uttar Pradesh University of Medical Sciences, Saifai, India)

Chapter 19. Oxidative Stress and Antioxidant Status in Pregnancy
(Parag A. Pathade and Vinod A. Bairagi, KBHS College of Pharmacy, Malegaon, India)

About the Editors

Index

Keywords: Antioxidants, Oxidative stress, Hypertension, Diabetes, Smoking

This book is suitable for professionals, academicians, students, researchers, scientists and industrialists around the world. Biomedical, health, and life science departments can use this book as a crucial textbook. Researchers and scientist from research institutes can use this book as efficient research info. Nutritionists, pharmacists, physicians, and other healthcare professionals can use this book as a complete reference book. Furthermore, for interested readers, this book is a storehouse of knowledge to comprehend the mechanisms of oxidant/antioxidant altering factors accountable for cell injury.

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