Overactive Bladder (OAB): Prevalence, Risk Factors and Management


Elvira Larson (Editor)

Series: Renal, Metabolic and Urologic Disorders
BISAC: MED088000

Overactive Bladder Syndrome (OAB) is a clinical entity characterised by urgency, with or without increased urinary frequency and/or urgency incontinence. It is a chronic condition with a high prevalence that increases with age, thus being a growing health problem especially in developed countries due to increased life expectancy. Patients with this disorder are often reluctant to seek advice due to embarassment, fear of social exclusion or the belief that symptoms are an expected consequence of ageing. Costs associated with treatments, use of pads/diapers and general economic burden are expected to increase in the future. OAB has a negative impact on quality of life (QoL) in varying degrees, depending upon the severity of symptoms and the presence of urgency incontinence. It has been linked to increased risk of fractures, institutionalization and depression in older populations particularly prone to the development of OAB. This books discusses the prevalence, risk factors and management options available for OAB. (Imprint: Nova Biomedical)

Table of Contents

Table of Contents


Chapter 1. Overactive Bladder (OAB): Pathophysiology Epidemiology, and Treatment Options
Bárbara Padilla-Fernández, David Hernández-Hernández, Ruth Doherty, and David Castro-Díaz (Department of Urology, University Hospital of the Canary Islands, Tenerife, Spain, and others)

Chapter 2. The Epidemiology of Lower Urinary Tract Symptoms and Urinary Incontinence: A Critical Review of the Literature
Megan Solomon, Bertha Chen and Lisa Rogo-Gupta (Stanford University School of Medicine, Stanford, California, USA, and others)

Chapter 3. Overactive Bladder in the Pediatric Population
Sophie Ramsay, Anne-Sophie Blais, Geneviève Nadeau, Katherine Moore, and Stéphane Bolduc (Division of Urology, CHU de Québec-Université Laval, Québec, Canada)

Chapter 4. Current Updates on Overactive Bladder Management
Kirin K. Syed and Angelo E. Gousse (Bladder Health and Reconstructive Urology Institute, Miramar, FL, USA)

Chapter 5. Investigational and Promising Novel Therapeutics for the Overactive Bladder and Urgency Urinary Incontinence
Emilio Sacco and Riccardo Bientinesi (Urology Department, “Agostino Gemelli” Academic Hospital, Catholic University of Sacred Heart, Rome, Italy)

Chapter 6. Overactive Bladder (OAB): Is There a Place for Drugs Targeting the Purinergic Cascade?
M. Silva-Ramos, I. Silva, F. Ferreirinha, M. Faria, and P. Correia-de-Sá (Laboratório de Farmacologia e Neurobiologia, Center for Drug Discovery and Innovative Medicines (MedInUP), Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto, Serviço de Urologia, Centro Hospitalar do Porto (CHP), Porto, Portugal)

Chapter 7. Mirabegron for the Treatment of Overactive Bladder
Federica Laraud, Simone Ferrero and Umberto Leone Roberti Maggiore (Academic Unit of Obstetrics and Gynaecology, IRCCS AOU San Martino – IST, Genoa, Italy, and others)


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