Ovarian Cancer: The “Gynaecological Challenge” from Diagnostic Work-Up to Cytoreduction and Chemotherapy. Volume 2

$195.00$293.00

Christos Iavazzo – Metaxa Memorial Cancer Hospital, Piraeus, Greece
Alexandros Fotiou, MD – Metaxa Memorial Cancer Hospital, Piraeus, Greece
John Spiliotis, PhD – Department of Surgical Oncology and HIPEC, Athens Medical Centre, Athens, Greece; Department of Surgical Oncology and HIPEC, European Interbalkan Medical Centre, Thessaloniki, Greece

Series: Surgery – Procedures, Complications, and Results; Women’s Issues
BISAC: MED033000; MED085090; MED085110
DOI:https://doi.org/10.52305/ORTN4397

Ovarian cancer is one of the deadliest gynaecological cancers. In most cases, it is detected as an advanced tumor, since early diagnosis is challenging for most forms of the disease. Surgery and platinum-based compounds have been the mainstay of therapy for many years. The prognosis for ovarian cancer depends on the type of surgery and on the response to chemotherapy. Other regimens have little effect if the disease does not respond to platinum. However, several new therapies are emerging including bevacizumab and PARP-inhibitors, among others. This book provides a detailed body of information important to an understanding of the clinical aspects and management of such a challenging disease. The authors strive to provide the physician with insights and illustrations as well as useful tips and tricks for the everyday clinical practice. Several world-known experts in the field participated in this fruitful effort offering their knowledge and everyday experience, as well as valuable and original photos from their personal archives as well as the most recent and up-to-date guidelines in the field.

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Table of Contents

Preface

Chapter 1. Surgical Anatomy – Essential Knowledge for Ovarian Debulking
E. Chacón and L. Chiva
Department of Obstetrics and Gynecology, Clinica Universidad de Navarra, Pamplona, Spain

Chapter 2. The Role of Minimal Invasive Techniques for the Management of Ovarian Tumours
Rainer Kimmig, MD, PhD, Pawel Mach, MD, PhD and Paul Buderath, MD, PhD
West German Cancer Center, Department of Gynaecology and Obstetrics, University of Duisburg-Essen, Germany

Chapter 3. The Role of Minimal Invasive Surgical Techniques in Ovarian Cancer after Neoadjuvant Chemotherapy
Giovanni Scambia, MD, PhD, Rita Trozzi, MD, PhD, Lucia Tortorella, MD, PhD and Anna Fagotti, MD, PhD
Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Ginecologia Oncologica, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia

Chapter 4. The Role of Sentinel Lymph Node Dissection and ICG in Ovarian Cancer Patients
Evangelos Kanavos, MD
First Surgical Unit of IASO Thessalias, Larissa, Greece

Chapter 5. Surgical Debulking in Ovarian Cancer – Surgical Atlas
Christos Iavazzo¹, MD, MSc, PhD, FRCOG, Alexandros Fotiou¹, MD and John Spiliotis², MD, PhD
¹Department of Gynecologic Oncology, Metaxa Cancer Hospital of Piraeus, Piraeus, Greece
²Department of Surgical Oncology and HIPEC, European Interbalkan Medical Center, Thessaloniki, Greece

Chapter 6. Pelvic and Paraaortic Lymphadenectomy: Surgical Technique
Artem Stepanyan, MD, PhD
Gynecologic Oncology Service, NAIRI Medical Center, National Institute of Health, Yerevan, Armenia

Chapter 7. Colorectal Surgery in Ovarian Cancer Patients
Nikolaos Machairas and Stylianos Kykalos
2nd Department of Propaedeutic Surgery, Medical School, National and Kapodistrian University of Athens, Athens, Greece

Chapter 8. Upper Abdominal Cytoreduction for Advanced Ovarian Cancer
Aditi Bhatt¹, MS, MCh., Gaurav Goswami², MD and Olivier Glehen³ MD, PhD
¹Department of Surgical Oncology, Zydus Hospital, Ahmedabad, India
²Department of Radiology, Zydus Hospital, Ahmedabad, India
³Department of Surgical Oncology, Centre Hospitalier Lyon-sud, Lyon, France

Chapter 9. Cardiophrenic Lymph Node Dissection in Ovarian Cancer Patients
L. Chiva, MD, PhD, FACS, E. Chacon, MD, and F. Boria, MD
Department of Obstetrics and Gynecology, Clinica Universidad de Navarra, Pamplona, Spain

Chapter 10. Liver Resection in Ovarian Cancer Treatment
Stylianos Kykalos, MD, MSc, PhD, FACS and Nikolaos Machairas, MD, PhD, FACS
2nd Department of Surgery, National and Kapodistrian University of Athens, General Hospital of Athens “Laiko,” Athens, Greece

Chapter 11. Splenectomy and Distal Pancreatectomy in Ovarian Cancer Patients
Santiago Domingo¹, MD, PhD, Blanca Segarra¹, MD, PhD, Victor Lago¹, MD, PhD, Tiermes Marina², MD, PhD and Pablo Padilla¹, MD, PhD
¹Department of Gynaecology Oncology, Hospital Universitario y Politécnico La Fe, Valencia, Spain
²Department of Gynaecology Oncology, Hospital Clínic, Barcelona, Spain

Chapter 12. Complete Pelvic Peritonectomy and Modified Nerve-Sparing Posterior Exenteration in Advanced Ovarian Carcinoma: Techniques and Feasibility
Santiago Domingo¹, MD, PhD, Blanca Segarra¹, MD, PhD, Victor Lago¹, MD, PhD, Tiermes Marina², MD, PhD and Pablo Padilla¹, MD, PhD
¹Department of Gynaecology Oncology, Hospital Universitario y Politécnico La Fe, Valencia, Spain
²Department of Gynaecology Oncology, Hospital Clínic, Barcelona, Spain

Chapter 13. The Role of Urologists in Ovarian Cancer Debulking Surgery
George Koritsiadis, MD, FEBU, PhD, MSc, and Ilias Giannakodimos, MD
Department of Urology, General Hospital of Eleusina “Thriassio,” Eleusina, Greece

Chapter 14. Secondary Cytoreduction in Recurrent Ovarian Cancer
Pauline Wimberger, MD, PhD
Department of Gynecology and Obstetrics, Carl-Gustav-Carus University Dresden, TU Dresden, Dresden, Germany; National Center for Tumor Diseases (NCT/UCC), Dresden, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany; Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; Helmholtz-Zentrum Dresden – Rossendorf (HZDR), Dresden, Germany

Chapter 15. The Role of Chemotherapy in Epithelial Ovarian Cancer – Current Protocols
Praveena Idaikkadar, MB B Chir, MRCP and Agnieszka Michael, PhD, MRCP
Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK

Chapter 16. The Role of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Ovarian Cancer
John Spiliotis¹, MD, PhD, FASPSM, Alexandros Fotiou², MD, and Christos Iavazzo², MD, MSc, PhD
¹Department of Surgical Oncology and HIPEC, European Interbalkan Medical Center, Thessaloniki, Greece
²Department of Gynecologic Oncology, Metaxa Cancer Hospital of Piraeus, Piraeus, Greece

Chapter 17. The Role of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) in Ovarian Cancer
John Spiliotis¹, MD, PhD, FASPSM, Alexandros Fotiou², MD and Christos Iavazzo², MD, MSc, PhD
¹Department of Surgical Oncology and HIPEC, European Interbalkan Medical Center, Thessaloniki, Greece
²Department of Gynecologic Oncology, Metaxa Cancer Hospital of Piraeus, Piraeus, Greece

Chapter 18. Maintenance and Consolidation Therapy in Epithelial Ovarian Cancer
Athina Christopoulou, MD, PhD
Head in the Department of Medical Oncology, St Andrews General Hospital of Patras, Patras, Greece

Chapter 19. Novel Therapies for Ovarian Cancer Patients
Marinos Tsiatas, MD, PhD
Department of Medical Oncology, Athens Medical Center, Athens, Greece

Chapter 20. Treatment of Recurrent Ovarian Cancer
Pawel Mach, MD, PhD and Rainer Kimmig, MD, PhD
Department of Gynaecology and Obstetrics, West German Cancer Center, University of Duisburg, Essen, Germany

Chapter 21. The Challenges and Solutions of Running Clinical Trials in Advanced Ovarian Cancer: The ICON Trials Experience
Francesca Schiavone¹, PhD, Richard Kaplan, MD, PhD and Andrew Clamp², MD, PhD
¹MRC Clinical Trials Unit at UCL, Institute of Clinical Trials & Methodology, London, UK
²The Christie NHS Foundation Trust and University of Manchester, Manchester, UK

Chapter 22. Anaesthetic Management of Ovarian Cancer Patients
Dimitrios Vaikos, MD and Omiros Chalkeidis, MD
4th Surgery Clinic, European Interbalkan Medical Center, Thessaloniki, Greece

Chapter 23. The Role of Thromboprophylaxis in Ovarian Cancer Patients
Ilias Evmorfiadis¹, MD, PhD, and Magdalini Dadakaridou², MD, PhD
¹2nd Haematology Clinic of Metropolitan Hospital, Athens, Greece
²Department of Haematology, Metaxa Cancer Hospital of Piraeus, Piraeus, Greece

Chapter 24. Enhanced Recovery Protocols for Patients with Ovarian Cancer
Christina Persefoni Sidera¹, RN, MSc and Ioanna Kotsioumpa², RN, MSc
¹Specialist Oncology Nurse, Department of Surgical Oncology, Metaxa Cancer Hospital of Piraeus, Piraeus, Greece
²Specialist Interventional Radiology Nurse, Department of Surgical Oncology, Metaxa Cancer Hospital of Piraeus, Piraeus, Greece

Chapter 25. Management Approaches to Ovarian Cancer in Elderly Women
Moiad Alazzam¹, MD, Zeinab Obeid², MD, Sally Eltawab¹, MD, and Sarah Smyth³, MD
¹Department of Gynaecological Oncology, Oxford University Hospitals, Oxford, UK
²King Hussein Cancer Centre, Amman, Jordan
³Department of Obstetrics and Gynaecology, Oxford University Hospitals, Oxford, UK

Chapter 26. Nutrition: Essential Support in Ovarian Cancer Patients
K. A. Poulia, PhD
Laboratory of Dietetics and Quality of Life, Department of Food Science & Human Nutrition, School of Food and Nutritional Sciences, Agricultural University of Athens, Athens, Greece

Chapter 27. Genetic Counselling – The BRCA Status of Ovarian Cancer Patients
Theofanis Zagoras, MD
Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden

Chapter 28. Quality of Life and Sexual Function after the Diagnosis and Treatment of Ovarian Cancer
Panagiota A. Ntalkitsii and Chryssa N. Karakana, MD

Index

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