Organophosphates: Detection, Exposure and Occurrence. Volume 1: Impact on Health and the Natural Environment

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Series
: Environmental Remediation Technologies, Regulations and Safety
BISAC: SCI026000
DOI: https://doi.org/10.52305/IMSO3553

Organophosphates are widely used nowadays. They have applications as pesticides, drugs, plasticizers, flame retardants or chemical warfare agents. Their acute toxicity is ascribed to the inhibition of acetylcholinesterase, a key enzyme in the transmission of nerve impulses in animals. Their toxic effects are manifested by the accumulation of acetylcholine and can lead to paralysis or death. Organophosphates also inhibit the other enzymes playing important roles in various biochemical processes. Organophosphate poisoning therapy is based on the application of specific antidotes as well as non-specific and symptomatic procedures.

In this contribution, the authors overview the organophosphates’ impact on human health and the environment, their various applications, acute exposure and possible treatments. In Volume 1, special attention was given to the connection of organophosphate exposure to cancer, synaptic vulnerability and depression development. The current state of knowledge and the future perspectives regarding their use, regulations, fate in the environment, biomonitoring, routes of exposure and legislation are reviewed. The detection and remediation of organophosphates in the environment using ionic liquids, electrochemical oxidation, carbon materials and metal-organic frameworks are discussed in more detail. The applications of organophosphates as acaricides and flame retardants are also reviewed.

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Table of Contents

Preface

Chapter 1. Organophosphate Pesticides and Human Health: Current Knowledge and Future Prospects
(Sandra Petrović – Department of Physical Chemistry, “Vinča” Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia)

Chapter 2. Organophosphate Pesticides: Cytotoxicity, Genotoxicity and Current Treatment Strategies
(Andreja Leskovac – Department of Physical Chemistry, “Vinča” Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia)

Chapter 3. Low-Level Chronic Organophosphate Exposure Contributes to the Development of Synaptic Vulnerability
(Sanja Ivković – Department of Molecular Biology and Endocrinology, “Vinča” Institute of Nuclear Sciences, National Institute of Republic of Serbia, University of Belgrade, Belgrade, Serbia)

Chapter 4. Organophosphates and Depression
(Tamara Tasić and Tamara Lazarević-Pašti – Department of Physical Chemistry, “Vinča” Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia)

Chapter 5. Exposure to Organophosphates as a Risk Factor for Cancer
(Lidija Todorović – Laboratory for Radiobiology and Molecular Genetics, “Vinča” Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia)

Chapter 6. Organophosphates: Fate in the Environment, Biomonitoring, Analysis, and Legislation
(Lejla Klepo – Department of Chemistry, Faculty of Science, University of Sarajevo, Sarajevo, Bosnia and Herzegovina)

Chapter 7. Ionic Liquids as Promising Media in (Pre)analytical Treatments and Degradation of Organophosphate Pesticides
(Aleksandra Dimitrijević and Ana Jocić – Department of Physical Chemistry, “Vinča” Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia)

Chapter 8. Electrooxidative Removal of Organophosphates – A Combined Experimental and Theoretical Approach
(Danka Aćimović and Dragana Vasić Anićijević – Department of Physical Chemistry, “Vinča” Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia)

Chapter 9. Carbon Materials as Adsorbents for Organophosphate Pesticides in Aqueous Media – A Critical Overview
(Igor Pašti, Stefan Breitenbach, Christoph Unterweger, and Christian Fürst – University of Belgrade – Faculty of Physical Chemistry, Belgrade, Serbia, et al.)

Chapter 10. MOFs compounds as Effective Tools for Detection of Organophosphate Compounds
(Aleksandra Bondžić – Department of Physical Chemistry, “Vinča” Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia)

Chapter 11. Spiders and Organophosphate Pesticides
(Boris Dudić – Faculty of Biology, University of Belgrade, Belgrade, Serbia)

Chapter 12. Organophosphates as Flame Retardants
(Nebojša Potkonjak – University of Belgrade, Institute of Nuclear Sciences Vinča, National Institute of the Republic of Serbia, Belgrade, Serbia)

Index


Editor’s ORCID iD

Tamara Lazarević-Pašti – https://orcid.org/0000-0001-6220-2079

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