Oncogenes: Classification, Mechanisms of Activation and Roles in Cancer Development


Luciano Torres (Editor)

Series: Genetics – Research and Issues, Cancer Etiology, Diagnosis and Treatments
BISAC: SCI029000

An oncogene is a modified gene or a series of nucleotides that encode a protein and direct the cell to the development of a neoplastic phenotype. Usually, oncogenes are involved in tumor development and increase the possibility that the development of a cell directs towards cancer. In this book, the authors present current research in the study of the classification, mechanisms of activation and role in cancer development of oncogenes. Topics include the role of oncogenes in gynecological pathology; oncomirs as the next frontier of oncogenes affecting cancer etiology and tumor progression; the role of the epidermal growth factor receptor as a therapeutic target in glioblastoma and other malignancies; and tumor suppressors involved in DNA repair and carcinoprevention. (Imprint: Nova Biomedical )

Table of Contents

Table of Contents


Role of Oncogenes in Gynecological Pathology
(Ciro Comparetto, Franco Borruto, Division of Obstetrics and Gynecology, City Hospital, Azienda, Prato, Italy, and others)

The Classification, Mechanisms of Activation and Roles in Cancer Development of Oncogenes
(Patricio Barros-Núñez, Mónica Alejandra Rosales-Reynoso, Clara Ibet Juárez-Vázquez, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México)

Dicer and microRNAs: Oncomirs are the Next Frontier of Oncogenes Affecting Cancer Etiology and Tumor Progression
(Ha T. Nguyen, Mandi M. Murph, University of Georgia College of Pharmacy, Department of Pharmaceutical and Biomedical Sciences
Athens, GA, USA)

The Role of the Epidermal Growth Factor Receptor as a Therapeutic Target in Glioblastoma and Other Malignancies
(Andrej Pala, Christian Rainer Wirtz, Marc-Eric Halatsch, Department of Neurosurgery, University of Ulm School of Medicine, Albert-Einstein-Allee, Ulm, Germany)

Tumor Suppressors Involved in DNA Repair and Carcinoprevention
(Yasuko Kitagishi, Satoru Matsuda, Department of Environmental Health Science, Nara Women’s University Kita-Uoya Nishimachi Nara, Japan)


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