Table of Contents
Foreword
Preface
Section I: Basic and Regulatory Issues in NHP Preclinical Research
Chapter 1. Refinement of the Care and Use of NHPs in Biomedical Research
(Wenhao Chen, Pierre Daloze, Huifang Chen – Immunobiology & Transplant Science Center, Department of Surgery, Houston Methodist Research Institute, Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX 77030, USA, et al.)
Chapter 2. Ethics and Legal Regulation of Nonhuman primates (NHPs) in Canada
(Junzheng Peng – Cardiovascular phenotyping core facility, CRCHUM, University of Montreal, Montreal, Quebec, Canada)
Chapter 3. The Use of Nonhuman Primates: Ethics and Regulations in Europe
(Jan Langermans – Animal Science Department, Biomedical Primate Research Centre, Lange Kleiweg 161, 2288GJ Rijswijk, the Netherlands)
Chapter 4. Biological Basic Differences in the Human and NHPs
(Adam Deak, Zsuzsanna Bodo and Norbert Nemeth – Department of Operative Techniques and Surgical Research, Faculty of Medicine, University of Debrecen, Debrecen, Hungary, et al.)
Chapter 5. MHC In NHP: From the Perspective of Immunogenetics
(Natasja G. de Groot – Biomedical Primate Research Centre, Department of Comparative Genetics and Refinement, Rijswijk, the Netherlands)
Chapter 6. Nonhuman Primate Stem Cell Biology
(Jakub Zafar Qazi, Zafarullah, M and Huifang Chen – University of Montreal, Montreal, Quebec, Canada, et al.)
Chapter 7. NHP Models for Influenza
(Ed Remarque – Biomedical Primate Research Centre, Virology Department, Rijswijk, The Netherlands)
Section II. NHP Models in Preclinical Research
Chapter 8. Non-Human Primate Models of Human Autoimmune Diseases
(Jakub Zafar Qazi, Huifang Chen and Muhammad Zafarullah – Faculté de pharmacie, Pavillon Jean Coutu, Université de Montréal, Montréal, Quebec, Canada, et al.)
Chapter 9. Nonhuman Primate Models in Organ Transplantation
(Lijun Song – Laboratory of Experimental Surgery, Department of Surgery, CRCHUM, University of Montreal, Montreal, Quebec, Canada)
Chapter 10. Modelling Malaria in NHPs Between 1900-2000
(Erica Pasini – Biomedical Primate Research Centre, Parasitology Department, Rijswijk, The Netherlands)
Chapter 11. Viral Diseases in NHPs
(Roger le Grand, Jan Langermans – CEA-Université Paris Saclay-Inserm, UMR1184 « Immunology of viral infections and auto-immune diseases”, IDMIT Department, IBJF, France, et al.)
Chapter 12. NHP Models in Neurodegenerative Disorders Research
(Ingrid Philippens – Research group Neuroscience, Animal Science Department, Biomedical Primate Research Centre (BPRC), Rijswijk, The Netherlands)
Chapter 13. Nonhuman Primate Models of Parkinson’s Disease: Improvement in the Understanding of PD Progress and Development of Novel Therapy
(Wenlei Jiang – Laboratory of Experimental Therapeutics, University Health Network, Toronto, Ontario, Canada)
Chapter 14. NHP Models of Cardio-Cerebrovascular Diseases Research
(Junzheng Peng and Huifang Chen – Cardiovascular phenotyping core facility, CRCHUM, University of Montreal, Montreal, Quebec, Canada, et al.)
Chapter 15. Nonhuman Primate Models for Beta Cell Replacement in Diabetes Research
(Scott Hunter Oppler and Melanie L. Graham – Preclinical Research Center, Department of Surgery, University of Minnesota, Saint Paul, MN)
Chapter 16. Overview of Imaging Modalities for Nonhuman Primates
(Marieke Stammes – Biomedical Primate Research Centre, Parasitology Department, Rijswijk, the Netherlands)
Chapter 17. Genetic Engineering in Nonhuman Primates and its Impact on Medical Science
(Adam He and Wenhao Chen – Immunobiology & Transplant Science Center, Department of Surgery, Houston Methodist Research Institute, Institute for Academic Medicine, Houston Methodist Hospital, Houston, TX 77030, USA, et al.)
Chapter 18. The Role of Nonhuman Primate (NHP) in Drug Safety Assessment
(Junzheng Peng and Huifang Chen – Cardiovascular phenotyping core facility, CRCHUM, University of Montreal, Montreal, Quebec, Canada, et al.)
Chapter 19. The Nonhuman Primate as a Unique Model to Understand the Pathogenesis of Human Endometriosis
(Ivanela Kondova – Division of Pathology and Microbiology, Animal Science Depertment, Biomedical Primate Research Centre, 2288 GJ Rijswijk, The Netherlands)
Chapter 20. NHP Models of Cancers
(Xiaoya Duan and Yanxin Hu – School of Life Sciences, East China Normal University, Shanghai, China, et al.)
Chapter 21. Nonhuman Primates in Non-Clinical Development and Translational Research of Medicinal Products and Devices
(Kupa Bilolo – Houston Methodist Hospital, Houston, TX)
Chapter 22. Nonhuman Primate (NHP) Models in Lung Transplantation
(Junzheng Peng and Huifang Chen – Cardiovascular phenotyping core facility, CRCHUM, University of Montreal, Montreal, Quebec, Canada, et al.)
Chapter 23. Aging Research in Nonhuman Primates
(Corinna N. Ross – Department of Science and Mathematics, Texas A&M-San Antonio, Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio TX)
Index
