New Research on Cervical Cancer


George Z. Rolland (Editor)

Cervical cancer is a malignancy of the cervix. Worldwide, it is the second most common cancer of women. It may be present with vaginal bleeding but symptoms may be absent until the cancer is in advanced stages, which has made cervical cancer the focus of intense screening efforts. Most scientific studies point to human papillomavirus (HPV) infection responsible for 90% of the cases of cervical cancer. There are 7 most common types of HPV – 16, 18, 31, 33, 42, 52 and 58. Types 16 and 18 being the most common cause of the cancer. Treatment is with surgery (including local exicision) in early stages and chemotherapy and radiotherapy in advanced stages of the disease. This book presents cutting edge research in this field. This involves, programs for cancer screening, alternative approaches to cervical cancer prevention, HPV/Co-Infections and Host Genetic Profiles, Small Cell Carcinoma of the Uterine Cervix, Indicators of HPV-induced carcinogenesis, functional genomics as a tool for understanding cervical cancer, histone deacetylase inhibitors, Chinese women and cervical cancer and cervical cancer in Northeaster Thailand.

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Table of Contents

Table of Contents

1. Using Intervention Mapping in Program Development to Promote Cancer Screening.
A Hospital-Based Community Outreach Program to Promote Cervical Cancer Screening Among Chinese Women – From Needs Assessment, Intervention Development to Program Evaluation (Su-I Hou, Univ. of Georgia, USA)
pp. 1-46

2. Alternative Approaches to Cervical Cancer Prevention: Risk-Adapted Multimodal Laboratory Cervical Screening (Reinhard Bollmann, Alinda D. Varnai and Agnes Bankfalvi et al., Institute of Pathology and International Medical College, Germany)
pp. 47-61

3. Underlying Cervical Cancer Portray: From HPV/Co-Infections and Host Genetic Profiles to Gene Expression Signatures (Martin C. Abba and Carlos D. Golijow, National Univ. of La Plata, Argentina)
pp. 63-107

4. Small Cell Carcinoma of the Uterine Cervix: A Sibling of Small Cell Lung Carcinoma? (Haodong Xu, Univ. of Rochester Medical Center, USA and Hanlin L. Wang, Washington Univ. School of Medicine, USA)
pp. 109-127

5. The Protein p16INK4a as a Reliable Indicator of the HPV-Induced Carcinogenesis (Galina M. Volgareva, Larisa E. Zavalishina and Daria A. Golovina et al., N.N. Blokhin Cancer Research Center of the Russian Academy of Medical Sciences, Russia and The Russian Ministry of Health, Russia)
pp. 129-147

6. Structural and Functional Genomics as a Tool for the Understanding of the Molecular Basis of Uterine Cervical Cancer: Oncogenomics (Guelaguetza Vazquez-Ortiz, Mauricio Salcedo and Patricia Piña-Sanchez, Oncology Hospital National Medical Center, Mexico)
pp. 149-174

7. Histone Deacetylase Inhibitors Induce Growth Inhibition, Cell Cycle Arrest and Apoptosis in Human Cervical Cancer Cells
(Noriyuki Takai, H. Phillip Koeffler and Hisashi Narahara, Oita Univ., Japan and Cedars-Sinai Medical Center/UCLA School of Medicine, USA)
pp. 175-188

8. Chinese Women and Cervical Cancer
(Eleanor Holroyd)
pp. 189-216

9. Cervical Cancer in Northeastern Thailand
(Wannapa Settheetham-Ishida, Khon Kaen University, Thailand and Takafumi Ishida, Univ. of Tokyo, Japan)
pp. 217-232


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