New Developments in Myocardial Ischemia Research

Rosalinda Madonna, MD, PhD (Editor)
Institute of Cardiology and Laboratory of Experimental Cardiology, Center of Excellence on Aging – CESI, “G. d’Annunzio” University – Chieti, Italy

Series: Cardiology Research and Clinical Developments
BISAC: MED010000

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Volume 10

Issue 1

Volume 2

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Heart failure caused by atherosclerosis-associated myocardial ischemia is a major cause of morbidity and mortality in developed countries in spite of great progress in intervention and medications. Beta-blockers, angiotensin-converting enzyme (ACE), ventricular resynchronization therapy (biventricular pacing) and ventricular assist devices cannot fully prevent this disease. The research on possible alternative therapies, as well as novel strategies for non-invasive assessment of myocardial ischemia, continues actively in the 21st century and offers novel opportunities, some already in use through clinical practice.

This book offers topics related to diagnosis and therapy of myocardial ischemia for a wide range of researchers in both academia and in the clinical field, for both undergraduate and graduate level students. Studies ranging from stem cell-based therapies to new promising biomarkers associated with coronary artery disease are discussed in depth. Non-invasive assessment of myocardial perfusion (Cardiac Magnetic Resonance), as well as diagnostic and prognostic role of cardiopulmonary stress test, are also covered. Leading experts give educated insight on myocardial ischemia in each chapter.

It is envisioned that this book, with its proposition of diagnostic and therapeutic strategies for myocardial ischemia, will inspire a wide range of researchers and physicians towards new explorations and applications in the field of ischemic heart disease.
(Imprint: Nova Biomedical)

Preface
(Rosalinda Madonna)

Chapter 1: Stem Cells Sources for Cardiac Regeneration - Basic Principles and Route of Delivery
(Rosalinda Madonna, Institute of Cardiology and Laboratory of Experimental Cardiology, Center of Excellence on Aging – CESI, “G. d’Annunzio” University – Chieti)

Chapter 2: Cardiac Stem/Progenitor Cells and Cardiac Regeneration
(Daniel I. Bromage, Gaia Giovannelli, Rosalinda Madonna, Davidson Sean, The Hatter Cardiovascular Institute, London, United Kingdom, and others)

Chapter 3: Mesenchymal Stromal Cells and Cardiovascular Regeneration
(Daniel I. Bromage, Davidson Sean, Francesca Vera Renna, Rosalinda Madonna, The Hatter Cardiovascular Institute, London, United Kingdom, and others)

Chapter 4: Epicardial Adipose Tissue as a Source of Progenitor Cells for Cardiac Regeneration
(Daniel I. Bromage, Maria Anna Teberino, Davidson Sean, Rosalinda Madonna, The Hatter Cardiovascular Institute, London, United Kingdom, and others)

Chapter 5: Telomeres, Telomerase and Cardiac Regeneration
(Rosalinda Madonna, Francesca Vera Renna, Pamela Confalone, Institute of Cardiology and Laboratory of Experimental Cardiology, Center of Excellence on Aging – CESI, “G. d’Annunzio” University – Chieti)

Chapter 6: Endothelial Shear Stress and Myocardial Regeneration
(Sayed Nour, Centre d’Innovation, Orleans Val de Loire Technopole, 16-rue Léonard de Vinci, Orleans, France)

Chapter 7: New Biomolecular Aspects in Ischemic Heart Disease
(Maurizio Coronelli , Sara Bozzinì, Angela D'Angelo, Maurizio Framarin, Colomba Falcone, Department of InternaI Medicine and MedicaI Therapy, University of Pavia, Pavia, ItaIy, and others)

Chapter 8: Tako-Tsubo Syndrome
(Ferit Onur Mutluer, Van Region Research and Training Hospital, Turkey)

Chapter 9: Cardiopulmonary Stress Test in the Assessment of Ischemic Heart Disease
(Rosalinda Madonna and Maria Anna Teberino, Institute of Cardiology and Laboratory of Experimental Cardiology, Center of Excellence on Aging – CESI, “G. d’Annunzio” University – Chieti)

Chapter 10: The Role of in-vivo Cardiac Magnetic Resonance (CMR) in the Assessment of Myocardial Tissue Ischemia
(Cesare Mantini, Stefano Delli Pizzi, Antonio Raffaele Cotroneo, Domenico Mastrodicasa, Armando Tartaro, Department of Neuroscience, Imaging and Clinical Sciences, Institute of Radiology, Section of Diagnostic Imaging and Therapy–Radiology Division, G. d'Annunzio University, Chieti, Italy, and others)

Index

Audience: Medical doctors cardiologist or internists, scientists, medical students, academy researchers

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