New Aspects of Vitamin D Endocrinology

Pentti Tuohimaa (Editor)
University of Tampere, Finland, and others

Yan-Ru Lou (Editor)
University of Helsinki, Finland

Series: Nutrition and Diet Research Progress
BISAC: MED060000

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Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Calcidiol (25-hydroxyvitamin D3) has recently been found to possess various biological activities at physiological concentrations in different in vitro and in vivo systems. It binds to vitamin D receptor and exerts subsequent genomic events. The action of calcidiol is proven to be independent of 1α-hydroxylation by using pharmacological and genetic tools.

Thus, calcidiol appears to be a new calcipherol hormone. Epidemiological studies on the role of hormonal forms of vitamin D3 in chronic diseases are inconsistent. There are several reasons to this inconsistency; one of the reasons might be a non-linear dependency on calcidiol serum concentrations. This book discusses the biological aspects of vitamin d which have an affect on the functional aspects of the endocrine system. (Imprint: Nova Biomedical)

ABSTRACT

INTRODUCTION

THE NEW VITAMIN D ENDOCRINOLOGY

CALCIDIOL AND CHRONIC DISEASES

CALCIPHEROL HORMONES AND AGING

VITAMIN D HORMESIS

ACKNOWLEDGEMENTS

REFERENCES

INDEX

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