Pentti Tuohimaa (Editor)
University of Tampere, Finland, and others

Yan-Ru Lou (Editor)
University of Helsinki, Finland

Series: Nutrition and Diet Research Progress
BISAC: MED060000

Calcidiol (25-hydroxyvitamin D3) has recently been found to possess various biological activities at physiological concentrations in different in vitro and in vivo systems. It binds to vitamin D receptor and exerts subsequent genomic events. The action of calcidiol is proven to be independent of 1α-hydroxylation by using pharmacological and genetic tools.

Thus, calcidiol appears to be a new calcipherol hormone. Epidemiological studies on the role of hormonal forms of vitamin D3 in chronic diseases are inconsistent. There are several reasons to this inconsistency; one of the reasons might be a non-linear dependency on calcidiol serum concentrations. This book discusses the biological aspects of vitamin d which have an affect on the functional aspects of the endocrine system. (Imprint: Nova Biomedical)