Neuroimmunity and the Brain-Gut Connection

Aristo Vojdani, PhD (Editor)
Immunosciences Lab Inc, Los Angeles, CA, USA

Series: Functional Neurology
BISAC: MED056000

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Bi-directional communication between the central nervous system (CNS) and the enteric nervous system (ENS) occurs both in health and disease. Various CNS- and gut-directed stressors stimulate the brain-gut axis. Processes modulating responsiveness to stressors along the brain-gut axis involve neural pathways, the immunological, and endocrinological mechanisms. Disturbances at every level of neural control of the gastrointestinal tract can affect modulation of gastrointestinal motility, secretion, and immune functions as well as perception and emotional response to visceral events.

ENS function, central processing, and autonomic regulation play an important role in the brain-gut dialogue. Stress and emotions may trigger neuroimmune and neuroendocrine reactions via the brain-gut axis. Nutritional strategies may impact on the integrity and the expression of neurophysiological systems, and neuroimmunolgical interventions through diet and toxin reduction may provide potential support to address the growing concerns of environmentally induced brain disease and neurological autoimmune disorders. In this book, you will find an in-depth review of the brain-gut connection.
(Imprint: Nova Biomedical)

Introduction
pp. 1

Chapter 1
Neuroimmunity
(Gerry Leisman, The National Institute for Brain and Rehabilitation Sciences, Nazareth, Israel, Rehabilitation Sciences and Human Factors, ORT-Braude College of Engineering, Karmiel, Israel and Neurología Restaurativa, Universidad de Ciencias Médicas de la Habana, Facultad Manuel Fajardo, Havana, Cuba)
pp. 3-4

Section One: Neuroimmunity
pp. 5

Chapter 2
Neuroimmunity: The Immunology of the Mind-Body Connection
(Aristo Vojdani and Jama Lambert, Immunosciences Laboratories, Los Angeles, California and Cyres Laboratories, Phoenix, Arizona, United States of America)
pp. 7-20

Chapter 3
The Immune System, Mucosal Immunity and Intestinal Permeability to Macromolecules
(Aristo Vojdani and Jama Lambert, Immunosciences Laboratories, Los Angeles, California and Cyres Laboratories, Phoenix, Arizona, United States of America)
pp. 21-36

Chapter 4
Cell-Mediated Immunity
(Aristo Vojdani and Jama Lambert, Immunosciences Laboratories, Los Angeles, California and Cyres Laboratories, Phoenix, Arizona, United States of America)
pp. 37-54

Chapter 5
Natural Killer, T-Cell and B-Cell Function in Health and Disease
(Aristo Vojdani and Jama Lambert, Immunosciences Laboratories, Los Angeles, California and Cyres Laboratories, Phoenix, Arizona, United States of America)
pp. 55-76

Chapter 6
Neuroautoimmunity and its Origins, Mechanisms and Assessments
(Aristo Vojdani and Jama Lambert, Immunosciences Laboratories, Los Angeles, California and Cyres Laboratories, Phoenix, Arizona, United States of America)
pp. 77-92

Chapter 7
Crossing Barriers: Gut-to-Brain Lessons from Interdisciplinary Collaboration
(Aristo Vojdani and Jama Lambert, Immunosciences Laboratories, Los Angeles, California and Cyres Laboratories, Phoenix, Arizona, United States of America)
pp. 93-106

Chapter 8
Metabolic Diseases Driven by Immunoinflammation
(Aristo Vojdani, Immunosciences Laboratories, Los Angeles, California and Cyres Laboratories, Phoenix, Arizona, United States of America)
pp. 107-130

Chapter 9
Brain-Reactive Antibodies in Traumatic Brain Injury
(Aristo Vojdani, Immunosciences Laboratories, Los Angeles, California and Cyres Laboratories, Phoenix, Arizona, United States of America)
pp. 131-140

Chapter 10
The Role of Environmental Triggers in Neuroautoimmunity
(Aristo Vojdani and Jama Lambert, Immunosciences Laboratories, Los Angeles, California and Cyres Laboratories, Phoenix, Arizona, United States of America)
pp. 141-162

Chapter 11
Intestinal and Blood-Brain-Barriers: Interfaces between Health and Disease
(Aristo Vojdani and Joel Bautista, Immunosciences Laboratories, Los Angeles, California and Cyrex Laboratories, Phoenix, Arizona, United States of America)
pp. 163-184

Chapter 12
Epilogue: Brain and Gut, Clinically Speaking
(Aristo Vojdani and Joel Bautista, Immunosciences Laboratories, Los Angeles, California and Cyres Laboratories, Phoenix, Arizona, United States of America)
pp. 185-194

Section Two: Acknowledgments
pp. 195

Chapter 13
About the Author
pp. 197

Chapter 14
About the Immunosciences Laboratory, Los Angeles, CA, United States
pp. 201-204

Chapter 15
About Cyrex Labs, Phoenix, AZ, United States
pp. 205-208

Chapter 16
About the Book Series "Functional Neurology"
pp. 209

Section Three: Index
pp. 211

Index
pp. 213-228

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