Neurogenesis: Cell Biology, Regulation and Role in Disease


Alicia Moreno (Editor)

Series: Neuroscience Research Progress

In the first chapter of this fascinating book, the authors present an overview of the evidence that implicates a compromised neurogenic function in the neuropathology of AD, PD and HD and discuss whether treatments aimed at restoring adult neurogenesis might have therapeutic relevance for the treatment of these disorders.

In the second chapter, the authors focus on some of the important biological properties of neural stem cells (NSC) in the health and disease brain, addressing the role of ABC transporters in the regulation of NSC behavior. The authors of the third chapter review the effect of prenatal stress on offpsring development from the behavioral and neurobiological perspectives, including neurogenesis in the hippocampus. In the last chapter of the book, the author examine the neurogenic properties of melatonin, a major indoleamine of the pineal gland.
(Imprint: Nova Biomedical)


Table of Contents

Table of Contents

pp. vii-ix

Chapter 1
The Role of Adult Neurogenesis in Neurodegenerative Diseases
(Joana Gil-Mohapel, Division of Medical Sciences and UBC Island Medical Program, University of Victoria, Victoria, British Columbia, Canada)
pp. 1-72

Chapter 2
Role of ABC Transporters in the Regulation of Neural Stem Cell Biology and as Therapeutic Targets in CNS Diseases
(Ana Sofia Falcão, Cátia Gomes and Dora Brites, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Avenida Professor Gama Pinto, Lisbon, Portugal, and others)
pp. 73-112

Chapter 3
Influence of Prenatal Stress on Psychiatric Disorders and Involvement of Neurogenesis in the Etiology
(Hiroshi Abe, Noriko Hidaka, Chika Kawagoe, Kei Odagiri, Tetsuya Ikeda, Toshikazu Nishimori, and Yasushi Ishida, School of Psychological Science, Health Sciences University of Hokkaido, Kanazawa, Toubetsu, Ishikari, Hokkaido, Japan, and others)
pp. 113-142

Chapter 4
Role of Melatonin in Regulating Neurogenesis and Neurodegeneration
(Rachen Singhakumar, Kasima Ekthuwapranee, Parichart Boontem, Utcharaporn Kamsrijai and Piyarat Govitrapong, Research Center for Neuroscience, Institute of Molecular Biosciences, Mahidol University, Salaya, Nakornpathom, Thailand)
pp. 143-164

pp. 165-177


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