Neurodegenerative Diseases: Overview, Perspectives and Emerging Treatments

$275.00

Annette Simon (Editor)

Series: Neurology – Laboratory and Clinical Research Developments
BISAC: MED056000

Neurodegenerative diseases are widespread disorders, with prevalence increasing with age. The first chapter of this book discusses autophagy, a cellular tool for the elimination of proteins that accumulate in neurodegenerative disorders and have pathogenetic significance. Parkinson’s disease (PD) is one of the most common degenerative diseases of the central nervous system. Chapter Two examines evidence on impairment of social cognition in patients with PD. Chapter Three discusses how finding the molecular cause of the PD could contribute to early diagnosis, and facilitate the development of effective neuroprotective or modulatory drugs. The final chapter reviews the functional role of adult hippocampal neurogenesis in learning and memory, and how this form of structural plasticity is altered in neurodegenerative diseases known to involve cognitive impairment such as Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease. (Imprint: Nova Biomedical)

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Table of Contents

Preface

Chapter 1. Autophagy and Neurodegeneration
T. A. Korolenko, A. B. Pupyshev, T. I. Pospelova, O. B. Gritsyk, A. V. Panov, V. A. Vavilin, A. B. Shintyapina and M. A. Tikhonova (Institute of Physiology and Basic Medicine, Novosibirsk, Russia, and others)

Chapter 2. Parkinson’s Disease: Clinical Profile and Social Cognition
Antonia Mitkova, Rita B. Ardito, Lorys Castelli, Corrado Azzaro, Mauro Adenzato and Ivan Enrici (Psychology Research Laboratory, IRCCS Italian Auxiliary Institute, S. Giuseppe Hospital, Piancavallo, Italy, and others)

Chapter 3. A Molecular Basis of Neurodegeneration in Parkinson’s Disease
Jolanta Dorszewska, Marta Kowalska, Wiktoria Blaszczak and Wojciech Kozubski (Poznan University of Medical Sciences, Poznan, Poland)

Chapter 4. Potentiating Hippocampal Neurogenesis with Physical Exercise: A Non-Invasive Strategy to Prevent Cognitive Decline in Neurodegenerative Diseases?
Joana Gil-Mohapel, PhD (Division of Medical Sciences and UBC Island Medical Program, University of Victoria, Victoria, Canada)

Bibliography

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