Neurobiology of substance use disorders


Authors: Nehdia Hashemi, Nazish Imran, Muhammad Waqar Azeem, and Ahsan Nazeer
Page Range: 9-20
Published in: International Journal of Child and Adolescent Health, 16#1 (2023)
ISSN: 1939-5930

Table of Contents


While substance use disorders have an onset in childhood or adolescence, untreated substance use disorders typically progress into adulthood, growing in severity and becoming chronic, relapsing, and potentially fatal disorders. These behaviors that were traditionally viewed as stemming from poor “choices” appear to have strong neurobiological and genetic underpinnings. Understanding the causes of addiction and underlying neurobiological processes is an active area of research. Most of the current knowledge is derived from preclinical studies and animal models of addiction and the following is a brief review of the neurobiological basis of substance use disorders.

Keywords: Childhood, adolescence, behavior, substance use, substance use disorders

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