Details
Table of Contents
ABSTRACT
INTRODUCTION
STUDIES DISCUSSED IN THIS CHAPTER
NONHUMAN PRIMATE SPATIAL MAZE
CIRCADIAN ACTIVITY
BEHAVIORAL OR COGNITIVE CLASSIFICATION
PHMRI
RECEPTOR BINDING ASSAYS
CONCLUSION
ACKNOWLEDGEMENTS
REFERENCES
INDEX
Neurobiological Correlates of Behavioral and Cognitive Performance in Nonhuman Primates
$0.00
Gwendolen E. Haley and Jacob Raber
Oregon Health and Science University Portland, OR, and others
Series: Animal Science, Issues and Research
BISAC: SCI070000
Animals in experiments are traditionally grouped by experimental treatment. Although this is a valuable way to differentiate the groups, alternatively, groups can be distinguished based on cognitive performance. Performance based analysis can yield valuable insights, corresponding to behavior and/or cognition, that might not otherwise be observed. This book discusses a cohort of elderly female rhesus macaques who participated in a spatial food port maze navigational test. Circadian activity and pharmacological MRI (phMRI) were assessed in these monkeys in vivo and radioligand binding was assessed in post-mortem tissue. Based on cognitive performance in the spatial maze, the cohort of monkeys was divided into Good Spatial Performers (GSP) and Poor Spatial Performers (PSP). (Imprint: Nova)
