Neurobiological Correlates of Behavioral and Cognitive Performance in Nonhuman Primates

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Gwendolen E. Haley and Jacob Raber
Oregon Health and Science University Portland, OR, and others

Series: Animal Science, Issues and Research
BISAC: SCI070000

Animals in experiments are traditionally grouped by experimental treatment. Although this is a valuable way to differentiate the groups, alternatively, groups can be distinguished based on cognitive performance. Performance based analysis can yield valuable insights, corresponding to behavior and/or cognition, that might not otherwise be observed. This book discusses a cohort of elderly female rhesus macaques who participated in a spatial food port maze navigational test. Circadian activity and pharmacological MRI (phMRI) were assessed in these monkeys in vivo and radioligand binding was assessed in post-mortem tissue. Based on cognitive performance in the spatial maze, the cohort of monkeys was divided into Good Spatial Performers (GSP) and Poor Spatial Performers (PSP). (Imprint: Nova)

 

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Table of Contents

ABSTRACT

INTRODUCTION

STUDIES DISCUSSED IN THIS CHAPTER

NONHUMAN PRIMATE SPATIAL MAZE

CIRCADIAN ACTIVITY

BEHAVIORAL OR COGNITIVE CLASSIFICATION

PHMRI

RECEPTOR BINDING ASSAYS

CONCLUSION

ACKNOWLEDGEMENTS

REFERENCES

INDEX

 

Additional information

Binding