Geeta Deswal, PhD – Professor & Head of Department, Guru Gobind Singh College of Pharmacy, Haryana, India
Sweta Kamboj, PhD – Associate Professor, Guru Gobind Singh College of Pharmacy, Yamunanagar, Haryana, India
Ajmer Singh Grewal, PhD – Professor & Head of Department, Guru Gobind Singh College of Pharmacy, Haryana, India
Kumar Guarve, PhD – Principal & Professor, Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, India

Series: Research Progress in Alzheimer’s Disease and Dementia
BISAC: NAT034000; MED072000; SCI011000
DOI: https://doi.org/10.52305/SFHQ7263

This book explores the therapeutic potential of plant-derived bioactive compounds, known as phytoconstituents, in the prevention and treatment of Alzheimer’s disease (AD). As a progressive neurodegenerative disorder, AD is characterized by cognitive decline, memory loss, and behavioral changes, with current treatments providing only symptomatic relief. Given the limitations and side effects of conventional therapies, there is an increasing interest in natural compounds that offer neuroprotective benefits through diverse biological mechanisms. This comprehensive volume examines key classes of phytoconstituents, including polyphenols, flavonoids, terpenes, alkaloids, saponins, coumarins, phytosterols, and cannabidiol, highlighting their roles in combating oxidative stress, inflammation, and amyloid plaque formation. Special emphasis is placed on molecular mechanisms, bioavailability challenges, and innovative strategies such as nanotechnology-based drug delivery systems to enhance therapeutic efficacy. This book also explores emerging areas such as the gut-brain axis, the synergy of phytoconstituents, personalized phytotherapy based on genetic and epigenetic factors, and cutting-edge research on neuroprotective compounds like Ginkgo biloba. Supported by recent preclinical and clinical studies, this publication offers an evidence-based approach to harnessing nature’s cognitive defenders for Alzheimer’s prevention and treatment.

This book not only aims to enhance the academic understanding of phytoconstituents and their role in Alzheimer’s prevention and treatment but also seeks to inspire further research and innovation in the development of natural therapeutic strategies. Whether you are a student, researcher, or healthcare professional, it serves as an essential resource, offering a comprehensive exploration of plant-based neuroprotective compounds. With a strong foundation in phytochemistry, pharmacology, and clinical applications, it provides valuable insights for future advancements in natural products and Alzheimer’s disease management.