Natural Heterocycles: Extraction and Biological Activity

K. L. Ameta (Editor)
Faculty of Arts, Science & Commerce, Mody Institute of Technology & Science (Deemed University) Lakshmangarh, Sikar, Rajasthan, India

Saksit Chanthai (Editor)
Department of Chemistry, Faculty of Science, Khon Kaen University, Thailand

Series: Chemistry Research and Applications
BISAC: SCI013000

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Natural products in the plant kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. During the last few decades, research into biologically active natural heterocycles has advanced tremendously thanks to contributions from the fields of chemistry, life sciences, food science and material sciences.

With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening (HTS) techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development in the pharmaceutical industry. The present book covers the synthesis/extraction and biological evaluation of the naturally occurring heterocycles, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of natural products.
(Imprint: Nova)

Preface

About the Editors

Contributors

Chapter 1 - Annonaceous Acetogenins As a Model of Bioactive Heterocyclic Derivative Structures. Extraction and Biological Evaluation (pp. 1-20)
Adriana Neske, Elena Cartagena, Sonia Díaz, Alicia Bardón, Eduardo Alberto Parellada and Lilian Di Toto Blessing (Instituto de Química Orgánica, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, and Instituto de Química Física, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán, Ayacucho 471, Tucumán, Argentina)

Chapter 2 - Indazole Motifs in Hetrocyclic Compounds: A Bio-active Component (pp. 21-54)
Digambar D. Gaikwad, Archana D. Chapolikar, Chabutai S. Patil, Saroj R. Bembalkar, Maya V. Katariya, K. L. Ameta and Rajendra P. Pawar (Department of Chemistry, Govt. College of Arts & Science, Aurangabad; Department of Chemistry, Deogiri College, Aurangabad, and Department of Chemistry, FASC, Mody Institute of Technology & Science, Lakshmangarh, Rajasthan, India)

Chapter 3 - Essential Oils, Phytochemicals and Bioactivities of Piper caninum Blume (pp. 55-84)
Wan Mohd Nuzul Hakimi Wan Salleh, Farediah Ahmad and Khong Heng Yen (Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, Skudai, Johor, and School of Chemistry and Environment Studies, Faculty of Applied Sciences, Universiti Teknologi Mara (UiTM) Sarawak, Sarawak, Malaysia)

Chapter 4 - Marine Based Anticancer Agents – Apratoxin and Its Analogues (pp. 85-106)
N. C. Desai and Amit Dodiya (Division of Medicinal Chemistry, Department of Chemistry, (UGC NON-SAP & DST-FIST Sponsored),
Mahatma Gandhi Campus, Maharaja Krishnakumarsinhji Bhavnagar University, Bhavnagar, Gujarat, India)

Chapter 5 - Aurone: The Versatile Natural Product Having Biological Potential (pp. 107-128)
Chetna Ameta, Arpit Kumar Pathak and K. L. Ameta (Department of Chemistry, University College of Science, M L S University, Udaipur, and Department of Chemistry, FASC, Mody Institute of Technology and Science, Lakshmangarh, Rajasthan, India)

Chapter 6 - Ascorbic Acid and Furfurals in Chilli Pepper, Wine and Fruit Juice: The Non-Enzymatic Browning Study (pp. 129-164)
Jatesadaporn Yaisoongnern and Saksit Chanthai (Department of Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen, Thailand)

Chapter 7 - Natural Coumarin Motifs: Anticancer Agents (pp. 165-178)
Sunil U. Tekale, Sushama S. Kauthale, Rajita D. Ingle, Sanjay B. Ubale, Satish U. Deshmukh, K. L. Ameta and Rajendra P. Pawar (Department of Chemistry, Deogiri College, Aurangabad (MS), and Department of Chemistry, FASC, Mody Institute of Technology and Science, Rajasthan, India)

Chapter 8 - Natural Flavonoids: Assets for Life (pp. 179-200)
Shipra Bhardwaj and K. L. Ameta (Government P.G. College, Kota-324001, Rajasthan, and Department of Chemistry, FASC, Mody Institute of Technology & Science, Lakshmangarh, Rajasthan)

Chapter 9 - Anthocyanin and Total Phenolics in Hot Chilli Varieties with Their Polyphenol Oxidase and Peroxidase Activities (pp. 201-226)
Prapha Arnnok and Saksit Chanthai (Department of Chemistry, Banasthali University, Banasthali, and Department of Chemistry, FASC, Mody Institute of Technology and Science, Lakshmangarh, Rajasthan, India)

Chapter 10 - Carbazole and Azacarbazole with Cytotoxicity and Anti Mitochondrial Potential (pp. 227-250)
Sudesh Kumar, Priyanka Jain, K. L. Ameta and Dharma Kishore (Department of Chemistry, Banasthali University, Banasthali, and Department of Chemistry, FASC, Mody Institute of Technology and Science, Lakshmangarh, Rajasthan, India)

Chapter 11 - Extraction and Biological Evaluation of Some Flavonoids (pp. 251-274)
Seema Kothari, Shiv N. Paliwal and K. L. Ameta (Department of Chemistry, Pacific College of Engineering, PAHER University, Udaipur; Deparment of Chemistry, Career Point Technical Campus, Career Point University, Rajasthan, and Department of Chemistry, FASC, Mody Institute of Technology and Science, Rajasthan, India)

Chapter 12 - A Dibenzofuran: (+)-Usnic Acid: A Heterocyclic Natural Compound Isolated from Lichen Parmelia Perlata (pp. 275-282)
Anil K. Sharma and Kuldeep K. Sharma (Department of Chemistry, Jagannath University, Jaipur (Rajasthan), India)

Index

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