Table of Contents
Table of Contents
Preface
Chapter One
Epidemiology of Myotonic Dystrophy in the Molecular Era: Implications for Clinical Trials and Association Studies
(Roberto Massa, and Nicola Vanacore, Center for Neuromuscular Disorders, Department of Systems Medicine, University of Rome Tor Vergata, Rome Italy, and others)
Chapter Two
Detecting and Targeting RNA: Biomarkers and Therapy for Myotonic Dystrophy
(Nikolaos P. Mastroyiannopoulos, Andrie Koutsoulidou and Leonidas A. Phylactou, Department of Molecular Genetics, Function and Therapy, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus)
Chapter Three
Endocrine System Involvement in Myotonic Dystrophy: Emerging Interactions and Potential Therapeutic Strategies
(Chiara Terracciano and Elisabetta Bucci, Department of Systems Medicine, Division of Neurology, and Department of Experimental Medicine and Surgery, Division of Clinical Biochemistry, University of Rome Tor Vergata, Rome, Italy, and others)
Chapter Four
Central Nervous System Involvement in Myotonic Dystrophies
(Gabriella Silvestri, Anna Modoni, Maria Laura E. Bianchi, Camillo Marra, Department of Geriatrics, Neuroscience and Orthopedics, UCSC, Rome, Italy)
Chapter Five
Strategies for Neuromuscular Blockade in Patients with Myotonic Dystrophy
(Petr Stourac, and Olga Smekalova, Department of Paediatric Anaesthesiology and Intensive Care Medicine, Faculty of Medicine, University Hospital Brno, Brno, Czech Republic, and others)
Chapter Six
Functional Assessment and Rehabilitative Treatment in Myotonic Dystrophy Type 1
(Carmelo Chisari, Caterina Tramonti, Stefania Dalise, Federica Bertolucci, Bruno Rossi, Unit of Neurorehabilitation, Department of Neuroscience, University Hospital of Pisa, Italy)
Chapter Seven
Protein Kinase Inhibitors as Potential Therapeutic Agents to Ameliorate Pathogenesis of Myotonic Dystrophy Type 1 (DM1)
(Marzena Wojciechowska and Piotr Kozlowski, Polish Academy of Sciences, Institute of Bioorganic Chemistry, European Centre of Bioinformatics and Genomics (ECBiG), Poznan, Poland)
Chapter Eight
Variant Interrupted DMPK Alleles: Implications in the Pathogenesis and Molecular Diagnosis of Myotonic Dystrophy Type 1 (DM1)
(Santoro Massimo, Masciullo Marcella, Novelli Giuseppe and Botta Annalisa, Fondazione Don Carlo Gnocchi, Milan, Italy, and others)
Chapter Nine
Sleep and its Characteristics in the Myotonic Dystrophies
(Natan Gadoth, Arie Oksenberg, Sleep Disorders Unit, Loewenstein Hospital, Rehabilitation Center, Raanana, Israel, and others)
Chapter Ten
Respiratory and Sleep Disorders in Children with Myotonic Dystrophy
(James D. Tutor, and Brent Haberman, Programs in Pediatric Pulmonary and Sleep Medicine, University of Tennessee Health Science Center, Le Bonheur Children’s Hospital, and St. Jude Children’s Research Hospital, Memphis, TN, USA)
Index
