Mycosis Fungoides and Sézary Syndrome: Pathogenesis, Diagnosis and Treatment

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Xiaohui Zhang, MD, PhD (Editor) – Associate Member, Department of Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
Lubomir Sokol, MD, PhD (Editor) – Senior member, Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA

Series: Dermatology – Laboratory and Clinical Research
BISAC: MED017000
DOI: https://doi.org/10.52305/LFSE9103

Mycosis fungoides (MF) is the most common subtype of cutaneous lymphomas.  The initial diagnosis of MF is often difficult, particularly in the early stage, requiring arduous clinical and pathological workups with repeat skin biopsies. Differential diagnosis ranging from benign dermatoses to other hematolymphoid neoplasms can be tricky and extremely challenging. Clinical management and treatment vary widely among providers and institutions. This book is an up-to-date overview of MF, covering almost every aspect of the disease. The chapters encompass etiology, clinical workup and diagnosis, pathological diagnosis, clinical and pathological variants, differential diagnosis, treatment and prognosis, as well as the state-of-the-art understanding of the molecular genetics of MF. Pediatric MF and Sezary syndrome (SS) are also included for completeness in the book.

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Table of Contents

Preface

Chapter 1. Epidemiology and Pathogenesis of Mycosis Fungoides
(Rohit Sharma, Xiaohui Zhang – Department of Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, US)

Chapter 2. Clinical Features and Diagnostic Workup of Mycosis Fungoides
(Grace Wei, Jaclyn Abraham, Lucia Seminario-Vidal – Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, US)

Chapter 3. Pathological Features and Diagnosis of Mycosis Fungoides
(Xiaohui Zhang – Department of Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, US)

Chapter 4. Pathological Features of Mycosis Fungoides with Large Cell Transformation
(Pukhraz Basra, Priyatharsini Nirmalanantham, Ling Zhang – University Hospitals Cleveland Medical Center, Cleveland, OH, USA, et al.)

Chapter 5. Histopathological Differential Diagnosis of Early Mycosis Fungoides and Benign Dermatoses
(Jianping Cai – Dianon Systems/Laboratory Corporation of America, Tampa, FL, US)

Chapter 6. Clinical Variants of Mycosis Fungoides
(Sarah Moore, James Isom – Department of Dermatology and Cutaneous Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, US)

Chapter 7. Mycosis Fungoides in Pediatric and Adolescent Young Adult Patients
(Eva Niklinska, Lucia Seminario-Vidal – Vanderbilt University Medical Center, Nashville, TN, US, et al.)

Chapter 8. Molecular Genetic Updates of Mycosis Fungoides
(Hammad Tashkandi – Department of Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, US)

Chapter 9. Treatment of Mycosis Fungoides
(Brandon Cardon, David Aung-Din, Lucia Seminario-Vidal – Department of Dermatology and Cutaneous Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, US, et al.)

Chapter 10. Staging And Prognosis of Mycosis Fungoides
(Kerry Hennessy, Nicole Nagrani, Lucia Seminario-Vidal – Department of Dermatology and Cutaneous Surgery, University of South Florida, Tampa, FL, US, et al.)

Chapter 11. Clinical Features, Systemic Treatment, and Prognosis of Sézary Syndrome
(Ashley Rose, Lubomir Sokol – Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, US)

Chapter 12. Pathogenesis and Diagnosis of Sézary Syndrome
(Hailing Zhang – Department of Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, US)

Index

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