Molecular and Supramolecular Bioinorganic Chemistry: Applications in Medical Sciences

$130.00

Ana Lucia Ramalho Mercê (Editor) – Chemistry Dept., Univ. Federal do Paraná, Paraná, Brasil
Judith Felcman (Editor) – Pontifícia Univ. Católica do Rio de Janeiro, RJ, Brasil
María Angeles Lobo Recio (Editor) – Sanitary Engineering Dept. Univ. Federal de Santa Catarina, SC, Brasil

For those who are in the medical science area fighting diseases and intoxications on a daily basis, this book intends to bring some of the latest results written to a medical context. For students of chemistry and medical sciences, this book will help shed some light on, for instance, the role of metal ions in the environment of life and how sinister the consequences are of contaminations in the environment, mainly water and soils. Results in the scientific literature in Medical Sciences are seldom read by medical doctors. However, many results in Bioinorganic Chemistry and Biochemistry are straight linked to free radicals production and to some diseases, such as degenerative ones (Alzheimer, Parkinson, Wilson, etc.). Metal ions are now shown in the chemistry literature to play a vital role in these diseases. Therefore, external chemical effects, as well as biochemical (internal) effects have to be considered.

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Table of Contents

Table of Contents

Introduction pp.i-viii:

1. THE EVOLUTION OF CHEMOTYPES;pp. 1-28
(João José Rodiles Fraústo da Silva
(Centro de Química Estrutural Complexo Interdisciplinar, Instituto Superior Técnico, Lisboa, Portugal)

2. VITAMIN D3 AND ANALOGS AND THEIR COMPLEXES WITH METAL IONS;pp. 29-44
(Gilles Bouet and Mustayeen Ahmed Khan, Université d’Angers, Laboratoire SONAS, Faculté de Pharmacie, France)

3. AlUMINIUM AND MEDICINE;pp. 45-68
(Christopher Exley, Birchall Centre for Inorganic Chemistry and Materials Science, Lennard-Jones Laboratories, Keele Univ., Staffordshire, UK.

4. METALS, NEUROTOXICITY AND NEURODEGENERATIVE DISORDERS;pp. 69-82
(Bettina Platt, School of Medical Sciences, College of Life Sciences and Medicine, Univ. of Aberdeen, Institute of Medical Sciences, Foresterhill, Scotland, UK)

5. SUPRAMOLECULAR PORPHYRIN MODEL COMPOUNDS FOR CYTOCHROME P-450, CYTOCHROME-C OXIDASE AND PHOTOSYNTHETIC SYSTEMS;pp. 83-136
(Koiti Araki and Henrique Eisi Toma, Instituto de Química, Universidade de São Paulo, Brazil)

6. METAL COORDINATION: A STRATEGY FOR DRUG DESIGN;pp. 137-220
(Heloisa Beraldo, Departamento de Química, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil)

Index pp.221-244

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