Mitophagy and Its Role in Health and Disease

$230.00

Shalini Mani, PhD – Associate Professor, Department of Biotechnology, Jaypee Institute of Information Technology, Noida, Uttar Pradesh
Samiksha Wasnik, PhD – Assistant Professor of Research, Division of Regenerative Medicine, Loma Linda University, Loma Linda, CA USA

Series: Cell Biology Research Progress
BISAC: SCI049000; SCI003000
DOI: https://doi.org/10.52305/ZKBP1526

Discover the fascinating world of mitophagy and its profound implications in aging, diseases, and therapeutic interventions. In this book a team of leading experts delves into the intricate mechanisms and far-reaching effects of mitophagy in a variety of medical conditions.

The book begins with an insightful overview of mitophagy, laying the foundation for a comprehensive exploration of its role in aging cardiomyopathy, cardiovascular diseases, neurological disorders, and neurodegenerative diseases. Moving forward, the book addresses the growing interest in natural remedies. It investigates the role that herbs play in promoting mitophagy to cope with disorders. Readers will explore the therapeutic potential of herbs, and the effects of yoga, opening new avenues for treatment and management.

Readers will gain a deep understanding of how this selective degradation and recycling process affects these medical conditions and how it can potentially be targeted for therapeutic interventions. With current understanding and future perspectives, readers will grasp the significance of mitophagy in various biological processes and the potential implications for enhancing cell function and overall well-being in older adults.

Mitophagy and its Role in Health and Disease is a one-of-a-kind resource that brings together cutting-edge research, in-depth analysis, and future perspectives on mitophagy. This book holds tremendous value for researchers, medical professionals, and students seeking to expand their knowledge regarding the role of mitophagy in aging, disease processes, and therapeutic interventions.

Don’t miss the chance to embark on a riveting journey into the world of mitophagy and its profound impact on human health.

Table of Contents

Preface

Chapter 1. Overview of Mitophagy
Shashi Prakash Singh¹, Madhu Rani², Annu Devi³, Rashmi Kumari², Moshahid Alam Rizvi², and Anil Kumar⁴
¹Pharmacology and Therapeutics, Centre for Genetics and Pharmacology, Roswell Park Comprehensive Cancer Care Buffalo, NY, USA
²Genome Biology Laboratory, Department of Biosciences, Jamia Millia Islamia, New Delhi, India
³Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India
⁴Directorate of Education, Rani Lakshmi Bai Central Agricultural University, Jhansi, Uttar Pradesh, India

Chapter 2.
Aging Cardiomyopathy: The Role of Mitophagy
Dinesh D. Anandani¹, Pranali Chandurkar¹, Nitu L. Wankhede¹, Shubhada V. Mangrulkar¹, Manjit B. Chauhan¹, Brijesh G. Taksande¹, Aman B. Upaganlawar², Milind J. Umekar¹, and Mayur B. Kale
¹Smt. KishoritaiBhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India
²SNJB’s ShrimanSureshdada Jain College of Pharmacy, Neminagar, Chandwad, Nashik, Maharashtra, India

Chapter 3. Mitophagy in Cardiovascular Diseases
Saboor Khan, Aditi Kaushik, and Shalini Mani
Department of Biotechnology, Jaypee Institute of Information Technology, Noida, Uttar Pradesh, India

Chapter 4. Mitophagy in Neurological Disorders
Aishani Kulshreshtha¹, Prashant Kaushik¹, Avinav Agarwal¹, Harshita Saxena¹, Rupesh Kumar¹, and Shazia Haider²
¹Department of Biotechnology, Jaypee Institute of Information Technology, Noida, Uttar Pradesh, India
²Department of Biosciences, Jamia Millia University, New Delhi, India

Chapter 5. Mechanisms and Role of Mitophagy in Neurodegenerative Diseases
Rashmi Kumari¹,², Madhu Rani¹, Siya Ram², Moshahid Alam Rizvi¹, and Anil Kumar³
¹Genome Biology Laboratory, Department of Biosciences, Jamia Millia Islamia, New Delhi, India
²Indira Gandhi National Open University, Department of Life Sciences, New Delhi, India
³Directorate of Education, Rani Lakshmi Bai Central Agricultural University, Jhansi, Uttar Pradesh, India

Chapter 6. Mitophagy in Carcinogenesis and Cancer Therapy
Madhu Rani¹, Rashmi Kumari¹,², Moshahid Alam Rizvi¹, Siya Ram², and Anil Kumar³
¹Genome Biology Laboratory, Department of Biosciences, Jamia Millia Islamia, New Delhi, India
²Indira Gandhi National Open University, Department of Life Sciences, New Delhi, India
³Directorate of Education, Rani Lakshmi Bai Central Agricultural University, Jhansi, Uttar Pradesh, India

Chapter 7. Mitophagy in Aging Muscle: Current Understanding and Future Perspectives
Kshitij B. Mankar¹, Pranali Chandurkar¹, Nitu L. Wankhede¹, Shubhada V. Mangrulkar¹, Manjit B. Chauhan¹, Brijesh G. Taksande¹, Aman B. Upaganlawar², Milind J. Umekar¹, and Mayur B. Kale¹
¹Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India
²SNJB’s Shriman Sureshdada Jain College of Pharmacy, Neminagar, Nashik, Maharashtra, India

Chapter 8. Mitophagy and Aging
Divya Jindal, Vinayak Agarwal, and Manisha Singh
Department of Biotechnology, Jaypee Institute of Information Technology, Noida, Uttar Pradesh, India

Chapter 9.
Mitophagy and Age-Associated Diseases
Aanchal Verma and Shalini Mani
Department of Biotechnology, Jaypee Institute of Information Technology, Noida, Uttar Pradesh, India

Chapter 10. Triggering Mitophagy: A Promising Approach to Overcome Chemoresistance in Cancer Therapy
Pragya Singh, Ankita Tayal, and Shalini Mani*
Department of Biotechnology, Jaypee Institute of Information Technology, Noida, Uttar Pradesh, India

Chapter 11.
A Workout for the Brain to Trigger Mitophagy
Aditi Kaushik, Saboor Khan, Ankita Tayal, and Shalini Mani
Department of Biotechnology, Jaypee Institute of Information Technology, Noida, Uttar Pradesh, India

Chapter 12. Role of Herbs on Mitophagy to Treat Neurodegenerative Disorders
Kaushlendra Kumar¹, Ashok Kumar Tiwari², and Rachana²
¹Department of Biotechnology, Delhi Technological University, New Delhi, India
²Department of Biotechnology, Jaypee Institute of Information Technology, Noida, Uttar Pradesh, India

Chapter 13. Therapeutic Tools for Mitophagy
Vinayak Agarwal, Divya Jindal, and Manisha Singh*
Department of Biotechnology, Jaypee Institute of Information Technology, Noida, Uttar Pradesh, India

Chapter 14.
Therapeutic Interventions in Mitophagy
Arup Kumar Misra¹ and Siddhartha Dutta²
¹Department of Pharmacology, All India Institute of Medical Sciences, Mangalagiri, Andhra Pradesh, India
²Department of Pharmacology, All India Institute of Medical Sciences, Rajkot, Gujarat, India

Chapter 15. Mitophagy and Stem Cells
Annu Devi¹, Madhu Rani², Shashi Prakash Singh³, Rashmi Kumari², Asmita Bharti⁴, Moshahid Alam Rizvi², and Anil Kumar⁵
¹Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India
²Genome Biology Laboratory, Department of Biosciences, Jamia Millia Islamia, New Delhi, India
³Pharmacology and Therapeutics, Centre for Genetics and Pharmacology, Roswell Park Comprehensive Cancer Care, Buffalo, NY, USA
⁴Department of Biochemistry, Indira Gandhi National Open University, Department of Biochemistry,
New Delhi, India
⁵Directorate of Education, Rani Lakshmi Bai Central Agricultural University, Jhansi, Uttar Pradesh India

Chapter 16. Mitophagy and Lung Cancer
Ashok Kumar Tiwari¹, Devatman Jauhari¹, Debdarshan Dutta¹, Dhruv Sharma¹, Priyanka¹, Harshit Devtalla¹, Nilay Solanki², Megha Chouhan¹, and Rachana R¹
¹Department of Biotechnology, JIIT, Noida, Uttar Pradesh, India
²Department of Pharmacology, Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, Changa, Gujarat, India

Index


Editor’s ORCID iD

Shalini Mani: 0000-0003-2500-6962
Samiksha Wasnik: 0000-0001-6097-0517

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