Mitogen-Activated Protein Kinases (MAPKs): Activation, Functions and Regulation

Charles K. Hester (Editor)

Series: Cell Biology Research Progress
BISAC: SCI008000



Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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Mitogen-Activated Protein Kinases (MAPKs): Activation, Functions and Regulation opens with a summary of the present knowledge about MAPK, with special emphasis on p38 and c-Jun N–terminal kinase. The authors focus on how these signaling pathways are engaged during some infections with intracellular parasites.

The authors also describe selected regulatory aspects of circadian clocks in vertebrates, exploring an intriguing link to MAPK. Circadian clocks are time-tracking systems that provide organisms with a survival advantage.

Cadmium, one of the toxic metals, is an important occupational and environmental pollutant that damages various organs, especially the kidney. The concluding study proposes that the type of kidney cell and severity of cadmium-induced cellular stress appear to determine the effect of MAPK on cell fate.
(Imprint: Nova)


Chapter 1. P38 and JNK as Targets of Protozoan Parasites to Manipulate Host Immune Response and Survive inside Host Cells

Chapter 2. Roles of MAPKs in Circadian Clock Regulation in Vertebrates

Chapter 3. Toxicological Significance of MAPK Activation in Cadmium-Induced Kidney Cell Death


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