Mifepristone: Pharmacology, Medical Uses and Potential Side Effects

Ariana Moore (Editor)

Series: Pharmacology – Research, Safety Testing and Regulation
BISAC: MED071000

Clear

$95.00

Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

eBook

Digitally watermarked, DRM-free.
Immediate eBook download after purchase.

Product price
Additional options total:
Order total:

Quantity:

Details

Mifepristone is a steroid compound derived from the estrane progestins. This compound strongly binds to the progesterone and glucocorticoid receptors, and to a lesser extent to the androgen receptor. As a result, this drug has a potent antiprogesterone, antiglucocorticoid and weak antiandrogen actions. Its main use as an abortifacient is due to the block of progesterone action which increases the uterine contractility, sensitizes the myometrium to prostaglandins, and elicits cervical maturing. This book discusses mifepristone on a vascular level, and provides the advantages and disadvantages of antiglucocorticoid and antiprogesterone activity of mifepristone. It also discusses the beneficial effects that this anitprogestin has in breast cancer. (Imprint: Nova Biomedical )

Preface

Chapter 1 - Mifepristone in the Cardiovascular System: Pharmacology, Regulation and Medical Uses (pp. 1-26)
Joana Feiteiro, Ignacio Verde and Elisa Cairrão (CICS-UBI – Centro de Investigação em Ciências da Saúde, Universidade da Beira Interior, Covilhã, Portugal)

Chapter 2 - Indications of Mifepristone in Ectopic Pregnancy (pp. 27-50)
María Teresa Gómez García, Esther López Del Cerro, Rocio Moreno Selva, Jessica Nogueira García, Carmen Callejón Rodríguez and Gaspar González Merlo (Obstetrics and Gynecology Department of the University and Hospital Complex of Albacete, Spain, and others)

Chapter 3 - Role for Mifepristone in Breast Cancer (pp. 51-70)
Caroline A. Lamb, Ana Sahores, John P. Lydon, Alfredo Molinolo and Claudia Lanari (Laboratory of Hormonal Carcinogenesis, IBYME-CONICET, Buenos Aires, Argentina, and others)

Chapter 4 - Mifepristone Blocks Progesterone-Induced Cell Proliferation and Migration in Human Astrocytoma Cells (pp. 71-84)
Liliana Germán-Castelán, Aliesha González-Arenas, Valeria Hansberg-Pastor and Ignacio Camacho-Arroyo (Facultad de Química, Departamento de Biología, Universidad Nacional Autónoma de México, Ciudad Universitaria, México, DF, México)

Index

You have not viewed any product yet.


SHOW ALL OF MY RECENTLY VIEWED BOOKS