Microspheres: Technologies, Applications and Role in Drug Delivery Systems


Leonardo Fernandes Fraceto (Editor)
State University of Sao Paulo, Brazil

Daniele Ribeiro de Araújo, PhD (Editor)
Federal University of ABC – UFABC, Brazil

Series: Materials Science and Technologies
BISAC: TEC021000

The book presents to the reader an interdisciplinary vision of microspheres including its concepts and applications. The book ranges from the preparation of microspheres using different methodologies (such as sol-gel processes) through different characterization techniques as well as the use of these systems for diagnostic diseases (cancer and hemodynamics fields). In addition, this book discusses aspects of the use of microspheres in: i) catalysis and separation sciences; ii) theoretical studies for applications in optical devices; iii) development of new systems aiming biomedical applications and iv) development of carrier systems for bioactive compounds.

Thus this book covers a wide range of areas such as physics, chemistry, mathematics, biology, biomedical engineering, medical, and food, among others. This book presents new advances in the use of microspheres and, in this way, we intend to contribute to students, teachers, researchers, research centers, companies, and industries which have interest in these topics. The book is organized into eleven chapters written in a clear and concise form with illustrations that will help readers comprehend all subjects. Furthermore, this book will contribute to the generation of knowledge in this field. (Imprint: Nova)



Table of Contents


Chapter 1 – Synthesis and Applications of Templated Sol-Gel Microspheres (pp. 1-32)
Mariana Ornelas, Carlos M. Pereira and Manuel Azenha (CIQ-UP, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Portugal)

Chapter 2 – Fabrication and Functionalization of Polymer Microspheres for Application in Catalysis and in Separation Science (pp. 33-94)
Adeniyi S. Ogunlaja, Ryan S. Walmsley and Zenixole R. Tshentu (Department of Chemistry, Nelson Mandela Metropolitan University, Port-Elizabeth, and Research & Development Division, Sasol Technology (Pty) Ltd, Sasolburg, South Africa)

Chapter 3 – Microspheres for the Multiplex Assay of Biomolecules Using Miniaturized Devices and Surface-Enhanced Raman Scattering (pp. 95-114)
Inseong Hwang and Taek Dong Chung (The Research Institute of Basic Sciences, Seoul National University, Department of Chemistry, Seoul National University, Seoul, South Korea)

Chapter 4 – The Narrow Transmission Resonances, Field Confinement and Green Function of a Multilayered Microsphere with Negative-Index Metamaterials Defects (pp. 115-136)
Gennadiy Burlak, A. Diaz-de-Anda and M. Nájera-Villeda (Centro de Investigación en Ingeniería y Ciencias Aplicadas, Universidad Autónoma del Estado de Morelos, Cuernavaca, Mor., México)

Chapter 5 – Magnetic Nanostructures for Biomedical Applications (pp. 137-160)
Perla E. García Casillas, Imelda Olivas Armendariz, Christian Chapa Gonzalez, Karen Castrejon Parga and Carlos A. Martínez Pérez (Instituto de Ingeniería y Tecnología, Universidad Autónoma de Ciudad Juárez, Ave. del Charro #610, Col. Partido Romero, Ciudad Juárez, Chihuahua, México)

Chapter 6 – Microspheres for Bone Regeneration (pp. 161-180)
Roger Borges, Luis A. Genova and Juliana Marchi (Centro de Ciência e Tecnologia de Materiais, Instituto de Pesquisas Energéticas e Nucleares, São Paulo, SP, and Centro de Ciências Humanas e Naturais, Universidade Federal do ABC, Santo André, SP, Brazil)

Chapter 7 – Milk Protein-Based Microspheres as Carriers for Encapsulating Bioactive Compounds (pp. 181-196)
Lu-E Shi, Wei Zheng, Zhen-Hua Li, Yong-Fang Jin, Yi-Fan Zhao and Zhen-Xing Tang (College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, Zhejiang, China and others)

Chapter 8 – Hemorrhagic Shock and Microsphere Deposition Method (pp. 197-208)
Bruno Schmidt and Luciano Zogbi (Federal University of Rio Grande – FURG, RS, Brazil)

Chapter 9 – Radiembolization with 90Y Microspheres in the Treatment of Liver Metastatic Disease from Breast Cancer (pp. 209-220)
R. Cianni, G. Pelle and M. D’Arienzo (Santa Maria Goretti Hospital, Latina, and National Institute of Radiation Metrology (ENEA), Rome, Italy)

Chapter 10 – Microspheres: Role in Drug Delivery Applications (pp. 221-244)
Baljit Singh (Department of Chemistry, Himachal Pradesh University Shimla, India)

Chapter 11 – Development of Liposomes Loaded with Charged Articaine Using Experimental Design (pp. 245-256)
Nathalie Ferreira Silva de Melo, Eneida de Paula, Tatiane Pasquoto, Renata de Lima, Daniele Ribeiro de Araújo, André Henrique Rosa and Leonardo Fernandes Fraceto (Department of Environmental Engineering, São Paulo Sate University, Sorocaba; Department of Biochemistry, Campinas State University, Campinas; Department of Biotechnology, São Carlos Federal University, Campus Sorocaba, Sorocaba, and Federal University of ABC, Santo André, São Paulo, Brazil)


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