Metabolomics and Clinical Approach

$230.00

Sevgi Durna Daştan – Associate Professor, Department of Biology, Division of Molecular Biology, Faculty of Science, Sivas Cumhuriyet University, Sivas, Turkey
Taner Daştan, PhD – Faculty of Science and Department of Biochemistry, Sivas Cumhuriyet University, Sivas, Turkey

Series: Biochemistry and Molecular Biology in the Post Genomic Era
BISAC: MED008000; MED009000; MED107000
DOI: https://doi.org/10.52305/FZMO0355

Metabolomics is the scientific study of chemical processes involving metabolites, substrates, intermediates, and namely all reagents and products of cell metabolism. Metabolomics and Clinical Approach will contribute to the the large-scale scientific study of small molecules within cells, biofluids, tissues or organisms and their interactions within a biological system. Also this book gives a perspective about study steps of metabolomics, the relationship of different diseases and metabolites, and the use of metabolomics in the treatment processes of different clinical pictures and diseases in the light of current information obtained from the literature. This book aims to describe all types of contents, effects, and kinetics of metabolite production related with metabolomics, as well as to summarize from the beginning to the end. Because the significance of metabolomics science and clinical trials increases day by day. Some diseases like cancer are an important cause of mortality for which no definitive treatment has yet been found. Further investigation of the relationship between metabolomics and diseases will open new horizons for diagnosis and treatment of many kind of diseases. This book presents all about metabolomics from the beginning to the end, as many kind of studies, potential mechanisms, diagnosis techniques, the metabolomics technologies like GC-MS, LC-MS, and software programmes about metabolomics analysis.

Table of Contents

Preface

Chapter 1. The Concept of Metabolomics
Sinan Vıcıl1, PhD and Tünay Karan2, PhD
1Department of Biochemistry, Tekirdag Namık Kemal University, Tekirdag, Turkey
2Department of Genetics, Yozgat Bozok University, Yozgat, Turkey

Chapter 2. Metabolomics and BMI
Bade Ertürk Arik, MD
Department of Family Physician, Istikbal Family Health Center, Kayseri, Turkey

Chapter 3. Metabolites Associated with Age and Aging
Ali Sağlik, MD
Department of Emergency Medicine, Faculty of Medicine, Istinye University, Istanbul, Turkey

Chapter 4. Geno-Metabolomics: Genotype Effects on Metabolites
Şeyda Kaya, PhD
Department of Medical Services and Techniques, Health Services Vocational School, Gaziantep Islam Science and Technology University, Gaziantep, Turkey

Chapter 5. Pharmaco-Metabolomics: Drug Effects on Metabolites
Eda Sonmez Gurer, PhD
Department of Pharmacognosy, Faculty of Pharmacy, Sivas Cumhuriyet University, Sivas, Turkey

Chapter 6. The Use of HPLC in Metabolomics Research
Tunay Karan1 and Sinan Vicil2
1Department of Genetics, Yozgat Bozok University, Yozgat, Turkey
2Department of Biochemistry, Namik Kemal University, Tekirdag, Turkey

Chapter 7. The Scope of LC-MS-Based Metabolomics
Pelin Koparir1, PhD and İnanç Baral2, PhD
1Department of Medical Services and Techniques, Health Services Vocational School, Fırat University, Elazıg, Turkey
2Department of Zootechnics and Animal Nutrition, Faculty of Veterinary Medicine, Sivas Cumhuriyet University, Sivas, Turkey

Chapter 8. Databases for Metabolomics Research
Dilek Arslan Ateşşahin1, PhD and Yusuf Muhammed Durna2, MD
1Department of Plant and Animal Production, Baskil Vocational School, Firat University, Elazığ, Turkey
2Department of Otolaryngology and Head and Neck Surgery, Private Practice, Istanbul, Turkey

Chapter 9. Metabolomic Research: Past, Present, and Future
Gonca Gulbay, PhD
Department of Medical Biology, Faculty of Medicine, Ordu University, Ordu, Turkey

Chapter 10. Metabolomics in Traumatic Brain Injuries
Mustafa Karademir, MD
Department of Neurosurgery, Sivas Cumhuriyet University, Faculty of Medicine, Sivas, Turkey

Chapter 11. The Clinical Impact and Use of Metabolomics in Diabetes Research
Melike Mercan Başpinar, MD
Department of Family Medicine, University of Health Sciences Gaziosmanpaşa Training and Research Hospital, Istanbul, Turkey

Chapter 12. The Current State and Future Perspectives of Metabolomics in Orthopedics
Anıl Aydin, MD
Department of Orthopedics and Traumatology, Erciyes University, Kayseri, Turkey

Chapter 13. Metabolomics and Metabolic Profiling in Embryos for Viability Assessment
Savaş Karakuş, MD
Department of Obstetrics and Gynecology, Cumhuriyet University School of Medicine, Turkey

Chapter 14. Metabolomics in the Diagnosis of Pregnancy Complications
Nazan Yurtcu and Dilay Karademir
Department of Obstetrics and Gynecology, Sivas Cumhuriyet University, Sivas, Turkey

Chapter 15. Metabolomic Markers and Their Clinical Uses in Neurology
Gülay Soykök, MD
Department of Neurology, Kayseri City Hospital, Kayseri, Turkey

Chapter 16. Metabolomics in Immunology Research
Semih Dalkiliç, PhD and Lütfiye Kadioğlu Dalkiliç, PhD
Department of Molecular Biology, Firat University, Elazig, Turkey

Chapter 17. The Clinical Uses of Mass Spectrometry-Based Approaches in Neurology and Psychiatry
Suna Dagli Atalay, MD
Department of Neurology, Kayseri Training and Research Hospital, Kayseri, Turkey

Chapter 18. Nutritional Metabolomics and Their Implications in Clinical Studies
Semra Türkoğlu, PhD
Department of Nutrition and Dietetics, Health Sciences Faculty, Firat University, Elazığ, Turkey

Chapter 19. Metabolome in Urology Practices: Signatures in Plasma and Urine
Aydemir Asdemir, MD
Department of Urology, Faculty of Medicine, Sivas Cumhuriyet University, Sivas, Turkey

Chapter 20. Metabolomic Applications in Food Science and Nutrition
Ayse Burcu Aktas, PhD
Department of Biochemistry, Faculty of Science, Sivas Cumhuriyet University, Sivas, Turkey

Chapter 21. The Use of Metabolomics in Neonatology
Murat Doğan, MD
Department of Pediatric Emergency, Kayseri City Hospital, Kayseri, Turkey

Chapter 22. Metabolomic Profiles of Body Fluids in Preterm Births
Seda Yilmaz Semerci, MD and Adviye Cakil Saglik, MD
Department of Neonatology, Pediatrics, University of Health Sciences, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey

Chapter 23.  The Use of Metabolomics in Diagnosing and Evaluating Inborn Metabolism Errors
Adviye Cakil Saglik, MD
Department of Neonatology, Pediatrics, University of Health Sciences, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey

Chapter 24. Metabolomics in Biomarker Identification for Cardiovascular Diseases
Mesude Avci, PhD
Department of Chemical Engineering, Sivas Cumhuriyet University, Sivas, Turkey

Index

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