Management of Diabetes Mellitus Based on Natural Products

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Yachana Mishra, PhD – Associate Professor, School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab, India
Vijay Mishra, PhD – Professor, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India

Series: Natural Products and Therapeutics; Endocrinology Research and Clinical Developments
BISAC: MED004000; MED022000
DOI: https://doi.org/10.52305/JCWM1341

The most prevalent endocrine condition, diabetes mellitus (DM), is characterized by underutilization of glucose, elevated blood sugar levels, and an ineffective or insufficient insulin secretory mechanism. DM is a severe health issue that affects 3% of the global population and 5% of the people in the US. Each year, it accounts for around 5% of all fatalities worldwide. Type 2 diabetes affects more than 90% of diabetic patients, whereas type 1 affects the remaining 10%. Today the management of diabetes without any side effects is still a challenge. Herbal drugs are prescribed widely because of their effectiveness, fewer side effects and relatively low cost. Numerous active principles produced from plants have proven to have anti-diabetic properties. Herbal treatments for diabetes have been used in patients with insulin-dependent and non-insulin-dependent diabetes, diabetic retinopathy, diabetic peripheral neuropathy, etc. Various plants can lower glucose production, promote glucose utilization, and combat secondary complications. This book will provide an updated, comprehensive resource of information on diabetes mellitus and its treatment by natural products. We believe this book will be of value to clinicians, biochemists, public health authorities, medical laboratory sciences technologists, biotechnologists, pharmaceutical and medical students, and fellows in training.

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Table of Contents

Preface

Acknowledgement

Chapter 1. Diabetes Mellitus: Worldwide Statistics and Types
Vijay Mishra¹, Aishwarya Joshi¹, Neha Shrivastava¹ and Alaa A. A. Aljabali²
¹School of Pharmaceutical Sciences, Lovely Professional University, Phagwara (Punjab), India
²Department of Pharmaceutics and Pharmaceutical Technology, Yarmouk University, Irbid, Jordan

Chapter 2. The Pathophysiology of Diabetes Mellitus
Yachana Mishra, Aditi Chattaraj and Kajal
School of Bioengineering and Biosciences, Lovely Professional University, Phagwara (Punjab), India

Chapter 3. The Social Determinants of Diabetes
Yachana Mishra, Kajal and Aditi Chattaraj
School of Bioengineering and Biosciences, Lovely Professional University, Phagwara (Punjab), India

Chapter 4. Diabetes Mellitus in Pregnancy
Yachana Mishra
School of Bioengineering and Biosciences, Lovely Professional University, Phagwara (Punjab), India

Chapter 5. Current Treatment Methods for Diabetes Mellitus
Vijay Mishra and Abhigyan Ranjan
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India

Chapter 6. Oral Antidiabetic Agents
Vijay Mishra¹, Abhigyan Ranjan¹ and Murtaza M. Tambuwala²
¹School of Pharmaceutical Sciences, Lovely Professional University, Phagwara (Punjab), India
²Lincoln Medical School, University of Lincoln, Brayford Pool, Lincoln, England, UK

Chapter 7. Molecular Targets and the Mechanisms of Antidiabetic Agents
Sumit Roy, Archita Dutta, Paranjeet Kaur, Manish Vyas and Sanjeev Kumar Sahu
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara (Punjab), India

Chapter 8. Sodium-Glucose Co-Transporter 2 Inhibitors in Diabetes
Yachana Mishra¹ and Vijay Mishra²
¹School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, India
²School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, India

Chapter 9. Chemical Scaffolds as Antidiabetic Agents
Charanjit Kaur and Sanjeev Kumar Sahu
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, India

Chapter 10. Phytoconstituents as Antidiabetic Agents and Their Chemical Aspects
Nancy Saini, Manish Vyas and Sanjeev Kumar Sahu
School of Pharmaceutical Sciences, Lovely Professional University, Phagwara (Punjab), India

Chapter 11. Natural Products in the Treatment of Diabetes: An Insight into the Mechanism of Action
Pranav Kumar Prabhakar¹ and Yachana Mishra²
¹Division of Research and Development, Lovely Professional University, Phagwara (Punjab), India
²School of Bioengineering and Biosciences, Lovely Professional University, Phagwara (Punjab), India

Chapter 12. A Targeted Therapeutic Approach Based on Medicinal Plants in the Management of Diabetes Mellitus
Pranav Kumar Prabhakar¹ and Yachana Mishra²
¹Division of Research and Development, Lovely Professional University, Phagwara (Punjab), India
²School of Bioengineering and Biosciences, Lovely Professional University, Phagwara (Punjab), India

Index

About the Editors

Editor’s ORCID iD

Yachana Mishra – 0000-0002-3467-0518
Vijay Mishra: 0000-0001-6542-2464

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