Mammary Glands: Anatomy, Development and Diseases


Edmund B. Rucker (Editor)
Department of Biology, University of Kentucky, Lexington, KY, USA

Series: Veterinary Science and Medicine
BISAC: SCI070000

This book is a compilation of manuscripts that encompass a breadth of information from different species including rodents, dogs, cows, goats and sheep. Normal developmental processes are covered and anatomical features are discussed, as well as the impact and significance of environmental chemicals and epigenetics on the mammary gland. In terms of disease states, cancer and mastitis are the most impactful in the fields of human medicine and livestock management, respectively, in the context of mammary gland biology. Therefore, this book presents in depth analyses of these diseases over several chapters and different model systems.

Rodent and canine cancer models are discussed, which are very relevant in understanding the roles that genes and the environment play in human breast cancer. In the livestock industry, mastitis in the dairy sector has a deep economic impact globally, and results in over a billion dollar loss annually. Several chapters are devoted towards this disease in dairy cattle, sheep and goats, with an underlying theme of generating newer detection strategies to detect infections at an earlier stage. An up-to-date description of the most important signaling pathways and mechanisms that impact both development and disease are included. A gamut of sub-disciplines are found throughout the book that covers the main aspects of anatomy, physiology, cell biology, genetics and molecular biology in both development and diseases of the mammary gland. (Imprint: Nova Biomedical )


Table of Contents

Table of Contents


Chapter 1. Post-Pubertal Mammary Gland Development: Morphology and Mechanisms
(Amber N. Hale and Edmund B. Rucker III, Department of Biology, University of Kentucky, Lexington, KY, USA)

Chapter 2. Mammary Gland Micro-Environment: From Stem Cells to Functional Mammary Glands
(Hai-Jun Huang, Xia Peng, Li Zhou, Shun Lu, Min Xiang, Yun-Guo Qian, Qi-Shuang Gao and Si-Wen Jiang, Department of Animal Biotechnology and Cell Engineering, Wuhan Institute of Animal and Veterinary Science, Wuhan Academy of Agricultural Science technology, Wuhan, People’s Republic of China)

Chapter 3. Environmental Chemicals and Mammary Gland Development
(Erin Pias Hines and Jennifer L Rayner, Office of Research and Development, National Center for Environmental Assessment, U.S. Environmental Protection Agency, RTP, NC, USA and others)

Chapter 4. Epigenetic Contributions to Mammary Gland Development and Breast Cancer Risk
(Kurt B. Hodges, Dana Bazzoun, Kimberly M. McDole, Rabih Talhouk and Sophie A. Leli¨¨vre, Department of Basic Medical Sciences and Center for Cancer Research, Purdue University, West Lafayette, IN, USA and others)

Chapter 5. Neoplastic Diseases of the Canine Mammary Gland
(Maria Isabel Carvalho, Teresa Raposo, Helena Rodrigues, Isabel Pires, Justina Prada and Felisbina L. Queiroga, Department of Veterinary Sciences, University of Tr¨¢s-os-Montes and Alto Douro; 5001-801 Vila Real, Portugal and others)

Chapter 6. Infection of the Lactating Mammary Gland: Current Status on the Molecular Biology of Mastitis
(Koen Breyne and Evelyne Meyer, Laboratory of Biochemistry, Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Belgium)

Chapter 7. Mastitis Resistance
(Mayumi Sugimoto, National Livestock Breeding Center, Odakurahara 1, Odakura, Nishigo, Fukushima, Japan)

Chapter 8. Indicators of the Mammary Gland Health Status in Dairy Animals
(Aneta Brodziak, Jolanta Kr¨®l, Piotr Stanek and Zygmunt Litwi¨½czuk, University of Life Sciences in Lublin, Poland)

Chapter 9. Effect of Lipopolysaccharide on Cell Populations in the Bovine Mammary Gland
(Petr Slama, Zdenek Havlicek and Jiri Skladanka, Departments of Animal Morphology, Physiology and Genetics, and Animal Nutrition and Forage Production, Mendel University in Brno, Czech Republic)



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