Living with Huntington’s Disease: Challenges, Perspectives and Quality of Life

Sherman Howell (Editor)

Series: Neuroscience Research Progress, Genetics – Research and Issues
BISAC: MED057000

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$95.00

Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Living with Huntington’s Disease: Challenges, Perspectives and Quality of Life first discusses the variety of sleep disorders in Huntington’s Disease, as well as how sleep quality can be associated with other important clinical symptoms.

Although Huntington’s disease is categorized as a movement disorder, the wide range of non-motor symptoms including cognitive impairment and behavioral abnormalities are considered by patients and their caregivers to be just as disabling as the motor symptoms. As such, the authors explore the importance of symptomatic treatment of Huntington’s disease-related symptoms.

Following this, the emotional and communicational issues in Huntington’s disease and their interrelations are examined, including depressive symptomatology, anxiety, helplessness or anger, as well as verbal and non-verbal communication and assistive technology.

Lastly, the authors describe current trends and efforts in gene therapy techniques and the improvements in health conditions of Huntington’s disease patients and their families.
(Imprint: Nova Medicine and Health)

Preface

Chapter 1. Sleep Problems in HD
(Natalia P. Rocha, Will K. Tanigaki, Maria A. Rossetti, Sudha S. Tallavajhula, and Erin Furr Stimming, Mitchell Center for Alzheimer's disease and Related Brain Disorders, Department of Neurology, University of Texas Health Science Center, Houston, TX, US, and others)

Chapter 2. Clinical Trials in HD: Lessons Learned, Progress, and Perspectives
(Natalia P. Rocha, Gabriela D. Colpo, Dylan May, Antonio L. Teixeira and Erin Furr Stimming, Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas Health Science Center, Houston, TX, US, and others)

Chapter 3. Emotional and Communicational Issues in Huntington's Disease
(Roman Adamczyk, PhD, Institute of Nursing, Faculty of Public Policies in Opava, Opava, Czech Republic)

Chapter 4. Gene Therapy as a Potential Decelerator of the Huntington’s Disease Progression
(Cristiani Folharini Bortolatto, Amália Gonçalves Alves, César Augusto Brüning, Evelyn Mianes Besckow, Luiz Roberto Carraro Junior, Jorge Mario Cárdenas Paredes, Rodolfo Baldinotti and Taís da Silva Teixeira Rech, Laboratory of Biochemistry and Molecular Neuropharmacology (LABIONEM), Post-Graduate Program in Biochemistry and Bioprospecting (PPGBBio), Center of Chemical, Pharmaceutical and Food Sciences, Federal University of Pelotas, Rio Grande do Sul, Brazil, and others)

Index

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