Liquid Chromatography: Principles, Technology and Applications

Fernando Ramos, PhD (Editor)
Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal

Series: Chemical Engineering Methods and Technology
BISAC: TEC009010

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Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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The versatility of liquid chromatography (LC) allows its applicability to countless areas. From the quality control of various industries, such as pharmaceutical, alimentary or chemistry, passing through health, environmental, toxicological or forensic activities, and also in the area of genetics or R&D; liquid chromatography applications are used worldwide. This book presents key support for everyone that works or intends to work in analytical fields, from students to senior researchers.

The principles of liquid chromatography, the new fluorinated stationary phases or how to achieve robustness, are examples of fundamental liquid chromatography issues that are discussed in the book. Furthermore reviews about the latest developments on the LC-MS/MS determination of antibiotic residues in food-producing animals or of emerging pollutants in environmental samples are presented, as well as liquid chromatography applications for the determination of vitamin E isomers in foods. Preparative liquid chromatography is also discussed, as is the role of liquid chromatography to evaluate food authenticity, namely milk and dairy products.

Last but not least, metabolomic and proteomic analysis, as well as serendipity are important issues that also benefit liquid chromatography utilization. The present book is truly innovating and, certainly, will be an important tool for those that are engaged in analytical science in all of the different areas of interest. (Imprint: Nova)

Preface pp. 1-ix

Chapter I - Principles of Liquid Chromatography
(Luis M.S. Loura, Faculdade de Farmácia, Universidade de Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, Coimbra, Portugal, and Centro de Química de Coimbra, Universidade de Coimbra, Rua Larga, Coimbra, Portugal)pp. 1-36

Chapter II - Fluorinated Stationary Phases on Liquid Chromatography: Preparation, Properties and Applications
(Oscar Núñez, Antonio Checa and Héctor Gallart-Ayala, Department of Analytical Chemistry, University of Barcelona, Martí i Franquès, Barcelona, Spain, and others)pp. 37-56

Chapter III - Robustness of Liquid Chromatographic Method: How to Achieve it and How to Confirm it?
(Biljana Jančić Stojanović, Tijana Rakić and Anđelija Malenović, University of Belgrade – Faculty of Pharmacy, Department of Drug Analysis, Belgrade, Serbia)pp. 57-98

Chapter IV - Liquid Chromatography: Review on the Last Developments on the Detection of Antibiotics in Food-Producing Animals
(Andreia Freitas, Sara Leston, Jorge Barbosa and Fernando Ramos, INRB-LNIV, Laboratório Nacional de Investigação Veterinária, Estrada de Benfica, Lisboa, Portugal, and others)pp. 99-140

Chapter V - Liquid Chromatography for the Determination of Tocopherols and Tocotrienols (Vitamin E) in Food of Plant Origin
(Emmanouil D. Tsochatzis, Maria Papageorgiou, Analytical Chemistry Laboratory, Department of Chemical Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece, and others)pp. 141-156

Chapter VI - Application of Preparative High-Performance Liquid Chromatography (HPLC): An Approach to the Isolation of the Nor-Neolignans from Styrax Pohlii
(Camila Spereta Bertanha, Ana Carolina Pereira, Márcio Luis Andrade e Silva, Wilson Roberto Cunha, Ana Helena Januário and Patrícia Mendonça Pauletti, Universidade de Franca, São Paulo, Brazil)pp. 157-172

Chapter VII - The Role of HPLC in the Authenticity Control of Milk and Dairy Products
(Victoria Samanidou, Eftichia Karageorgou and Paraskevi Kourti, Laboratory of Analytical Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece)pp. 173-206

Chapter VIII - Application of Liquid Chromatography to the Determination of Emerging Pollutants in Environmental Samples
(Cristina Mahugo-Santana, Zoraida Sosa-Ferrera and José Juan Santana-Rodríguez, Departamento de Química, Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain)pp. 207-238

Chapter IX - Recent Trends in Green Chromatography for the Analysis of Pharmaceuticals in the Aquatic Environment
(Heba Shaaban and Tadeusz Górecki, Department of Chemistry, University of Waterloo, Waterloo, Ontario, Canada, and others)pp. 239-268

Chapter X - Metabolomic Applications of Liquid Chromatography: From Food Bioactive Metabolites to Disease Biomarkers Research
(Jorge Pereira, João Gonçalves, Catarina L. Silva, Berta Mendes, Pedro Silva, Vera Alves, José Figueira and José S. Câmara, CQM - Centro de Química da Madeira, Centro de Ciências Exactas e da Engenharia da Universidade da Madeira, Campus Universitário da Penteada, Funchal, Portugal)pp. 269-290

Chapter XI - LC-MS Based Proteomic Analysis for Biofuel Production
(Xiaoling Tang, Benedict Jia Hong Lee and Wei Ning Chen, School of Chemical and Biomedical Engineering, College of Engineering, Nanyang Technological University, Singapore)pp. 291-298

Chapter XII - Serendipity, Psychopharmacology and High Pressure Liquid Chromatography
(Unax Lertxundi, Saioa Domingo-Echaburu and Rafael Hernandez, Pharmacy Service, Red de Salud Mental Araba, Araba, Spain, and others)pp. 299-306

Index pp. 307-322

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