Lipid Peroxidation: Inhibition, Effects and Mechanisms


Series: Chemistry Research and Applications
BISAC: SCI013000

This book presents an overview of lipid peroxidation: inhibition, effects and mechanisms. The topics analyzed, cover a broad spectrum of functions played by lipid peroxidation and presents new information in this area of research. The topics analyzed include: progress in the knowledge of lipid peroxidation, from the first evidences issued by Nicolas Theodore de Saussure in Paris 1804; fighting against lipid peroxidation: the unique story of docosahexaenoic acid in the brain; protective effects of melatonin and structurally-related molecules in reducing membrane rigidity due to lipid peroxidation; synergistic effects of antioxidant compositions during inhibited lipid autoxidation; lipid peroxidation and animal longevity; free radicals in health and disease; lipid peroxidation in autoimmune diseases; aldehydes derived from lipid peroxidation in cancer and autoimmunity; the role of reactive oxygen species and lipid peroxidation in the neurodegenerative process after spinal cord injury; kinetics and mechanisms of inhibited lipid autoxidation in presence of 4-substituted-coumarins; hypoxia and oxidative stress: cell signaling mechanisms and protective role of vitamin C and cilnidipine; characterization of oxidative stress and antioxidant potency; paying attention to time and location; lipid peroxidation in aquatic organisms: ontogenetic, phylogenetic and ecological aspects; chemistry of lipid oxidation in edible oils; and menopause progression and oxidative stress: associated mechanisms and the importance of physical exercise. (Imprint: Nova)

Table of Contents

Table of Contents

Chapter 1. Progress in the Knowledge of Lipid Peroxidation, from the First Evidences Issued by Nicolas – Theodore De Saussure in Paris 1804
Angel Catalá (Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas, (INIFTA-CCT La Plata-CONICET), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Argentina)

Chapter 2. Fighting against Lipid Peroxidation in the Brain: The Unique Story of Docosahexaenoic Acid
Mario Díaz, Verónica Casañas-Sánchez, Raquel Marín and José Antonio Pérez (Department of Animal Biology, Laboratory of Membrane Physiology and Biophysics, University of La Laguna, Tenerife, Spain, and others)

Chapter 3. Protective Effects of Melatonin and Structurally-Related Molecules in Reducing Membrane Rigidity Due to Lipid Peroxidation
J.J. García, L. López-Pingarrón, E. Esteban-Zubero, M.C. Reyes-Gonzales, J.O. Alda, D. Pereboom, R.J. Reiter (Department of Pharmacology and Physiology, University of Zaragoza, Zaragoza, Spain, and others)

Chapter 4. Synergistic Effects of Antioxidant Compositions During Inhibited Lipid Autoxidation
Vessela D. Kancheva and Silvia E. Angelova (Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia, Bulgaria)

Chapter 5. Lipid Peroxidation and Animal Longevity
A. J. Hulbert, Nicolas Martin and Paul L. Else (School of Biological Sciences, and School of Medicine, University of Wollongong, Wollongong, Australia)

Chapter 6. Free Radicals and Lipid Peroxides in Health and Disease
Naveen K. V. Gundala, Siresha Bathina and Undurti N. Das (BioScience Research Centre, GVP College of Engineering Campus, Visakhapatnam, India, and others)

Chapter 7. Lipid Peroxidation in Autoimmune Diseases: Friend or Foe?
Ana Reis and M. Rosário M. Domingues (School of Life and Health Sciences, Aston University, Birmingham, UK)

Chapter 8. Aldehydes Derived from Lipid Peroxidation in Cancer and Autoimmunity
Barrera G., Pizzimenti S., Daga M., Dianzani C., Cetrangolo G.P., Lepore A., Arcaro A., and Gentile F. (Department of Clinical and Biological Sciences, University of Turin, Torino, Italy, and others)

Chapter 9. The Role of Reactive Oxygen Species and Lipid Peroxidation in the Neurodegenerative Process after Spinal Cord Injury
Elisa García-Vences, Roxana Rodríguez-Barrera, Monica Goldberg, and Antonio Ibarra (Faculty of Health Sciences, Universidad Anahuac Mexico Norte, Av. Universidad Anahuac, Huixquilucan, Mexico City, Mexico, and others)

Chapter 10. Kinetics and Mechanism of Inhibited Lipid Autoxidation in Presence of 4-Substituted-Coumarins
Vessela D. Kancheva, Silvia E. Angelova, Adriana K. and Slavova-Kazakova (Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia, Bulgaria)

Chapter 11. Hypoxia and Oxidative Stress: Cell Signaling Mechanisms and Protective Role of Vitamin C and Cilnidipine
Kusal K.Das, Swastika Das and Jeevan G.Ambekar (Laboratory of Vascular Physiology and Medicine, Department of Physiology, Department of Chemistry, BLDEA’s V.P. Dr. P.G. Halakatti College of Engineering and Technology, Vijayapura, Karnataka, India, and others)

Chapter 12. Characterization of Oxidative Stress and Antioxidant’s Potency: Pay Attention to Time and Location
Dov Lichtenberg and Ilya Pinchuk (Dept of physiology and pharmacology, Tel Aviv University, Sackler Medical School, Ramat Aviv, Tel Aviv, Israel, and others)

Chapter 13. Lipid Peroxidation in Aquatic Organisms: Ontogenic, Phylogenic and Ecological Aspects
Rudneva I.I. and Shaida V.G. (The A.O. Kovalevskiy Institute of Marine Biological Research of RAS, Nahimov av., Sevasopol, Russia)

Chapter 14. Chemistry of Lipid Oxidation in Edible Oils
Alam Zeb (Department of Biotechnology, University of Malakand, Pakistan)

Chapter 15. Menopause Progression and Oxidative Stress: Associated Mechanisms and the Importance of Physical Exercise
Randhall Bruce and Kreismann Carteri (Federal University of Rio Grande do Sul Porto Alegre/Brazil)

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