Lipases and their Role in Health and Disease


Vasudeo P. Zambare, PhD – R&D and Technical Head, Balaji Enzyme and Chemical Ltd, Mumbai, India
Mohd. Fadhil Md. Din, PhD – Professor, Center for Environmental Sustainability and Water Security (IPASA) & Department of Water and Environmental Engineering, School of Civil Engineering, Universiti Teknologi Malaysia, Bahru, Malaysi; Director, Campus Sustainability, Universiti Teknologi Malaysia, Bahru, Malaysia

Series: Biochemistry Research Trends; Life Sciences Research and Development
BISAC: SCI007000; SCI010000; SCI000000

This comprehensive work illuminates the molecular foundations and applications of lipases, offering an understanding of their significance in human well-being as well as diseases. Chapter one begins with the meticulous exploration of lipase biochemistry. Chapter two delivers a move beyond digestion to explore the health benefits, metabolic influences, and therapeutic potential of lipases. Chapter three addresses the global issue of obesity. Readers gain insights into the diverse applications and sustainability of lipases, breaking down triacylglycerols in various industries. Probiotic isolates are explored for their role in preventing oxidative rancidity, improving shelf life, and serving as industrial biocatalysts in diverse bioconversion reactions. In Chapter four, the authors present an eco-friendly approach to surfactant synthesis, showcasing the environmental advantages over chemical counterparts. Chapter five delves into the multifaceted roles of lipases. In the last chapter the ubiquitous nature of lipases is underscored. These enzymes, produced by all living organisms, play crucial roles in digestion, transport, and processing of dietary lipids. This chapter navigates through the ubiquity of cellular enzyme lipases in diseased conditions in human, animals and birds and its adverse impact.

This book transcends the boundaries of conventional enzymatic literature. This pioneering work promises readers a holistic view of lipase biology, offering a profound understanding of their intricate mechanisms and multifaceted roles in health and disease.

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Table of Contents


Chapter 1. Overview on Lipases and Their Role in Health and Disease
Vasudeo Zambare¹,² and Mohd. Fadhil Md. Din²
¹R&D Department, Balaji Enzyme and Chemical Pvt. Ltd., Andheri (E), Mumbai, India
²Center for Environmental Sustainability and Water Security (IPASA) and Department of Water and Environmental Engineering, School of Civil Engineering, Universiti Teknologi Malaysia, Bahru, Malaysia

Chapter 2.
Lipase: Beyond Digestion – Exploring Health Benefits, Metabolic Influence, and Therapeutic Potential
Sandhya Mulchandani¹ and Pratik Kale²
¹Microbiology Department, Smt. Chandibai Himathmal Mansukhani College, Ulhasnagar, India
²K. J. Somaiya College, Mumbai, India

Chapter 3. Probiotic Lipases: Versatile Catalysts for Sustainable Industries and Therapeutic Innovations
Saraswathy Nagendran and Neha Mudaliar
SVKM’s Mithibai College of Arts, Chauhan Institutes of Science and Amrutben Jivanlal College of Commerce and Economics, Mumbai, India

Chapter 4. Bio-Surfactants: Green Synthesis Using Lipases and Role in Human Health
Benu Arora
Department of Applied Chemistry and Environmental Studies, Bhagwan Parshuram Institute of Technology, Guru Gobind Singh Indraprastha University, New Delhi, India

Chapter 5. Lipases: Guardians of Energy Metabolism and Beyond – Unveiling Therapeutic, Physiological, and Functional Frontiers
Gagandeep Kaur¹ and Vikas Sharma²
¹Chitkara School of Pharmacy, Chitkara University, Himachal Pradesh, India
²Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, India

Chapter 6. Lipases in Diseased Conditions – Impact on Humans, Animals and Birds
Sourabh Patil and Tushar Borse
School of Biotechnology, Vidya Pratishthan’s Arts, Commerce and Science College, Baramati, Pune, Maharashtra, India


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