Lipase: Functions, Synthesis and Role in Disease


Hamdi Sassi (Editor)
Sofien Cannamela (Editor)

Series: Biochemistry Research Trends, Biotechnology in Agriculture, Industry and Medicine
BISAC: SCI007000

Lipases are ubiquitous enzymes which catalyze the hydrolysis of triacylglycerols to glycerols and free fatty acids. Due to their characteristics of enantioselectivity and regioselectivity and stability in organic solvents, they have gained importance in industrial applications. In this book, the authors examine the functions, synthesis and role in disease of lipases. Topics discussed include the action of lipases as a biotechnological tool; fungal lipases in biocatalysis; secreted phospholipase A2 inhibitors from cynara cardunculus L. and aloe vera extract as a potential therapeutic drug for inflammatory diseases; lipoprotein lipase activity in sickle cell nephropathy; lipases in the pharmaceutical industry; and yeast cell surface display of lipases. (Imprint: Nova Biomedical )


Table of Contents

Table of Contents


Acquisition of New Properties under the Action of Lipases as a Biotechnological Tool
(Samia Soultani-Vigneron, Laurent Poisson, Françoise Ergan, Gaëlle Pencreac’h, Laboratoire Mer, Molécules, Université du Maine, Institut Universitaire de Technologie de Laval, Laval, France)

Synthesis of Acyl Saccharides and Ascorbates Using Immobilized Lipase in an Organic Solvent and Their Functionalities
(Yoshiyuki Watanabe, Takashi Kobayashi, Shuji Adachi, Department of Biotechnology and Chemistry, Faculty of Engineering, Kinki University, Umenobe, Takaya, Higashi-Hiroshima, Japan, and others)

Solvent-Free Biocatalytic Synthesis of Polyglycerol Polyricinoleate (PGPR) using Immobilized Candida Rugosa and Rhizopus Arrhizus Lipases
(S. Ortega, M.C. Montiel, M.F. Máximo, J. Bastida, Chemical Engineering Department, University of Murcia, Murcia, Spain)

Fungal Lipases: Versatile Tools for Biocatalysis
(Selmene Ouertani, Habib Horchani, Laboratoire de Biochimie et de Génie Enzymatique des Lipases, Sfax, Tunisie)

Secreted Phospholipase A2 Inhibitors from Cynara Cardunculus L. and Aloe Vera Extracts as a Potential Therapeutic Drug for Inflammatory Diseases
(Sofiane Bezzine, Youssef Gargouri, Laboratoire de Biochimie et de Génie Enzymatique des Lipases, Sfax, Tunisia)

Lipoprotein Lipase Activity in Sickle Cell Nephropathy: A Review
(Abiodun Mathias Emokpae, Department of Medical Laboratory Science, School of Basic Medical Sciences, College of Medical Sciences, University of Benin, Benin City, Department of Chemical Pathology, Aminu Kano Teaching Hospital, Kano, Nigeria)

Lipases in the Pharmaceutical Industry: An Approach for Racemic Drugs
(Fabiano Jares Contesini, José Valdo Madeira Junior, Gabriela Alves Macedo, Hélia Harumi Sato (Food Science Department, Faculty of Food Engineering, Campinas State University, SP, Brazil) and Patrícia de Oliveira Carvalho (Pharmacy Course, University São Francisco, Bragança Paulista, SP, Brazil)

Yeast Cell Surface Display of Lipases
(Evgeniya Y. Yuzbasheva, Tigran V. Yuzbashev, Ivan A. Laptev, Tatiana V. Vybornaya, Sergey P. Sineoky, Russian State Collection of Industrial Microorganisms (VKPM), State Research Institute of Genetics and Selection of Industrial Microorganisms, Moscow, Russia)

Microbial Lipases and their Applications in Structured Lipids
(José Valdo Madeira Junior, Fabiano Jares Contesini, Paula Speranza, Hélia Harumi Sato, Gabriela Alves Macedo, Patrícia de Oliveira Carvalho, Food Science Department, Faculty of Food Engineering, Campinas State University, SP, Brazil, and others)



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