Leptin and its Role in Health and Disease

$95.00 – $143.00

Stephen E. Bradley (Editor)

Series: New Developments in Medical Research
BISAC: MED000000

This book contains seven chapters that detail leptin and its role in health and disease. Chapter One discusses many features of leptin and emphasizes the significance of future research to better understand leptin’s involvement in neurological and behavioral disease causes and therapy. Chapter Two details the role of leptin as a biochemical marker. Chapter Three presents the consequences of hyperleptinemia caused by high leptin serum levels and leptin receptor resistance in obesity on renal, cardiac, vascular, and sympathetic nervous system function. The objective of Chapter Four is to shed light on the reproductive functions of leptin and its role in altered reproductive physiology. Chapter Five discusses the role of leptin in the pathogenesis and progression of diabetes and diabetic complications. Chapter Six summarizes the current understanding of the role of leptin in nutrition and cancer. Lastly, Chapter Seven provides a comprehensive review on the importance of leptin during different pathological conditions.

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Table of Contents

Preface

Chapter 1. The Physiological and Pathophysiological Role of Leptin in Neurological and Behavioral Disorders
Hayriye Soytürk1, PhD, Ümit Kılıç2, PhD and Ayşegül Yıldız3, PhD
1Bolu Abant Izzet Baysal University, Institute of Graduate Studies Interdisciplinary Neuroscience, Bolu, Türkiye
2Duzce University Vocational School of Health Services, Duzce, Türkiye
3Bolu Abant Izzet Baysal University, Medical School, Department of Physiology Bolu, Türkiye

Chapter 2. The Role of Leptin as a Biochemical Marker in Health and Disease
Hadi Karimkhani
Department of Biochemistry, School of Medicine, Istanbul Okan University, Istanbul, Türkiye
Department of Stem Cell, Institute of Health Sciences, Eskisehir Osmangazi University, Eskisehir, Türkiye

Chapter 3. The Effects of Leptin on the Cardiovascular System
Ümit Kılıç1, PhD, Hayriye Soytürk2, PhD, Eylem Suveren3, PhD and Ayşegül Yıldız4, PhD
1Duzce University Vocational School of Health Services, Duzce, Türkiye
2Bolu Abant Izzet Baysal University, Institute of Graduate Studies Interdisciplinary Neuroscience, Bolu, Türkiye
3Bolu Abant Izzet Baysal University, Faculty of Health Sciences, Department of Nursing, Bolu, Türkiye
4Bolu Abant Izzet Baysal University, Medical School, Department of Physiology Bolu, Türkiye

Chapter 4. Leptin in Reproductive Health and Disease
D. G. Kishor Kumar1, Ayushi Vaidhya1, C. L. Madhu1, Manjit Panigrahi2, T. U. Singh1, Dinesh Kumar1 and Subhashree Parida1
1Division of Pharmacology and Toxicology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India
2Division of Animal Genetics and Breeding, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India

Chapter 5. The Role of Leptin in Diabetes and Its Complications
Xiaoyu Xu1, Yigang Feng2, Cheng Zhang1, Ning Wang1 and Yibin Feng1
1School of Chinese Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong, China
2Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangzhou, China

Chapter 6. The Role of Leptin in Nutrition and Cancer
Hasan Gencoglu1, PhD and Kazim Sahin2, PhD
1Department of Biology, Faculty of Science, Firat University, Elazig, Türkiye
2Department of Animal Nutrition and Nutritional Disorders, Faculty of Veterinary Medicine, Firat University, Elazig, Türkiye

Chapter 7. A Molecular Overview of Leptin in Several Pathological Conditions
Muge Atis Ceylan and Hilal Eren Gozel
Department of Medical Biology and Genetics, Istanbul Okan University School of Medicine, Istanbul, Türkiye

Index

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