Leprosy: Epidemiology, Treatment Strategies and Current Challenges in Research


Roger S. Kopp (Editor)

Series: Allergies and Infectious Diseases
BISAC: MED022090

Leprosy is a chronic granulomatous infectious disease that affects the skin and peripheral nerves; its causative agent is the obligate intracellular bacillus Mycobacterium leprae. The etiological diagnosis of the disease in its paucibacillary (PB) form still needs to be improved, because the bacillus is not yet cultivable. This book discusses the current challenges in the research of leprosy, as well as the epidemiology and treatment strategies available. (Imprint: Nova Biomedical )

Table of Contents

Table of Contents


Chapter 1 – Leprosy: From Clinical Diagnosis to Benchwork (pp. 1-30)
M. J. F. Brochado, PhD., N. A. de Paula and A. M. Roselino, M.D. (Post Doctorate student, School of Medicine of Ribeirao Preto, University of São Paulo, Ribeirao Preto, Sao Paulo, Brazil, and others)

Chapter 2 – In Vivo and In Vitro Evidence on the Relationship between Antiphospholipid Antibodies and Leprosy (pp. 31-50)
Ricardo Forastiero and Marta Martinuzzo (Department of Physiology, Thrombosis and Hemostasis, Favaloro University, and others)

Chapter 3 – Leprosy and Pregnancy: A Epidemiological and Social Study in the Pará State, North of Brazil (pp. 51-70)
Vera Regina da Cunha Menezes Palácios, Cléa Nazaré Carneiro Bichara, Régis Bruni Andriolo, Mauro José Pantoja Fonteles, Brenda Nazaré Gomes Andriolo, Nélson Veiga Gonçalves and Marinete Marins Póvoa (Doctor in Biology of Infectious and Parasitic Agents at the Federal University of Pará (UFPA). Physician in Dermatologist. Coordinator in the Program of Medical Internship in Family Medicine of the State University of Pará (UEPA). Chief of the Communitarian Health Department (UEPA), Brazil)

Chapter 4 – The Potential of Antimicrobial Peptide Inhibitors (APIs) and Elicitors (APEs) in Leprosy Treatment (pp. 71-92)
Ernesto Prado Montes de Oca (In silico laboratory, Molecular Biology Laboratory, Biosafety Area, Medical and Pharmaceutical Biotechnology Unit, Research Center in Technology and Design Assistance of Jalisco State, National Council of Science and Technology (CIATEJ AC, CONACYT), Guadalajara, México)


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