Leiomyomas: Risk Factors, Clinical Manifestations and Treatment Options

Ayman Al-Hendy (Editor)
Division of Translational Research Department of Obstetrics and Gynecology, Medical College of Georgia, Georgia Regents University, GA, US

Salama Salama, PhD (Editor)
Department of Pharmacology and Toxicology, College of Pharmacy, Al-Azhar University, Cairo, Egypt

Series: Obstetrics and Gynecology Advances
BISAC: MED033000

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Volume 10

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Edited by premier researchers in the field, this is a unique book that comprehensively covers the important topic of uterine leiomyomas from biology, health disparity challenges, impact on fertility, novel risk factors, imaging as well as innovative minimally-invasive to non-invasive treatment options with over eleven chapters by leading practitioners and medical investigators of this disease. Although all areas of uterine leiomyoma are reviewed and updated, with a focus on the medical treatment of this common condition, which offers promise to millions of patients with symptomatic uterine leiomyoma.

This book describes important facets of this disease such as the role of vitamin D deficiency as a novel risk factor and its higher incidence in women of color. Novel approaches for treatment using green tea extract or radiofrequency volumetric thermal ablation are also described in detail. This book is essential reading for gynecologists, family doctors, physician assistants, nurse practitioners, medical students, OB/GYN residents and fellows, reproductive biologists, as well as other health care providers who care for women with this common disease.
(Imprint: Nova Biomedical)

Preface

Editors Contact Information

Chapter 1 - High Prevalence of Uterine Fibroids in Women of Color (pp. 1-12)
Torie C. Plowden, MD, MPH, Monica N. Modi, MD, Lisa Green, MD, MPH and Alicia Y. Armstrong, MD, MHSCR (Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, US and others)

Chapter 2 - Somatic Stem Cells in Leiomyoma Formation (pp. 13-30)
Aymara Mas, PhD and Carlos Simón, MD, PhD (Fundación Instituto Valenciano de Infertilidad, Instituto Universitario IVI- University of Valencia, INCLIVA, Valencia, Spain and others)

Chapter 3 - Obesity, Inflammation and Fibroids (pp. 31-44)
Monica N. Modi, MD, Charles Armstrong and William H. Catherino, MD, PhD (Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, Michigan, US and others)

Chapter 4 - Uterine Fibroids and Endometrial Dysfunction (pp. 45-66)
Sara A. Mohamed, MD, Waseem Khoder, MD and Ayman Al-Hendy, MD, PhD (Department of Obstetrics and Gynecology, Faculty of Medicine, Mansoura University, Mansoura, Egypt and others)

Chapter 5 - Imaging of Leiomyoma (pp. 67-102)
Penelope L. Moyle, MBChB(hons), MRCP, FRCR, Amir Helmy, Bsc, MBBS, MRCS, and Susan Freeman, BA(hons), MB, BChir, MRCP, FRCR (Department of Radiology, Cambridge University Hospital NHS Trust, Cambridge, United Kingdom)

Chapter 6 - Etiology, Clinical Manifestations, Evaluation and Management of Uterine Leiomyoma (pp. 103-124)
Mohammad Ebrahim Parsanezhad, MD and Bahia Namavar Jahromi, MD (Infertility Research Center, Department of OB-GYN, Division of Reproductive endocrinology and infertility, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran)
Free Download Available

Chapter 7 - Recent advances in Medical Treatment of Uterine Fibroids (pp. 125-150)
Heba M. Eltoukhi, MD and Ayman Al-Hendy, MD, PhD (Department of Obstetrics & Gynecology, Suez Canal University, Ismailia, Egypt and others)

Chapter 8 - Medical Adjuncts for the Surgical Management of Uterine Fibroids (pp. 151-174)
Innie Chen, MD, FRCSC, Catherine Allaire, Sukhbir S. Singh and George Vilos (Department of Obstetrics and Gynaecology, University of Ottawa; Department of Obstetrics and Gynaecology, University of British Columbia, and Department of Obstetrics and Gynaecology, Western University, Canada)

Chapter 9 - Radiofrequency Volumetric Thermal Ablation of Symptomatic Uterine Fibroids: The Acessa Procedure (pp. 175-192)
Bruce B. Lee, MD, Keith B. Isaacson, MD and Michael P. Diamond, MD (Halt Medical, Inc., Brentwood, California, US and others)
Free Download Available

Chapter 10 - Treatment of Uterine Fibroids by Temporary Transvaginal Uterine Artery Occlusion: A Concept to Consider Further? (pp. 193-198)
Jay M. Berman, MD, Elizabeth Puscheck, MD., MS, Michelle Yoscovits, BS, Karen Collins, MA, MS, Roy Collins, RN, MD and Michael P. Diamond, MD (Division of Gynecology,
Wayne State University, Detroit, Michigan, US and others)

Chapter 11 - Looking for New Druggable Targets in Uterine Fibroids (pp. 199-208)
Shahinaz Shalaby, MD, MSc and Ayman Al-Hendy, MD, PhD (Pharmacology Department, Tanta Medical School, Tanta University, Tanta, Egypt and others)

Index

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