Leg Ulcers and Chronic Wounds: Symptoms, Treatment and Prevention

Simon Green (Editor)

Series: New Developments in Medical Research
BISAC: MED076000



Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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A leg ulceration is a common, chronic, reoccurring condition. The majority of leg ulcers are due to venous and/or arterial disease. In this book, the future trends in the management of leg ulcers are discussed. The prognostic factors and risk factors are examined as well. Other chapters present a review on the impact of drugs commonly prescribed in clinical practices, and discuss their beneficial or detrimental role in chronic leg ulcers; a papain-based gel for the treatment of leg ulcers (papain is known for treating wounds of various etiologies and in several healing stages); compression therapy and ultrasound as therapy for leg ulcer treatment; an examination of the main antibiotics and antiseptics that are available for the therapeutic management of chronic leg ulcers, chronic wounds and the limitations of their use; and finally, the chapter provides the readers with a modulation of the foreign body response to treat chronic wounds.
(Imprint: Nova Biomedical)


Chapter 1
Leg Ulcers and Chronic Wounds: Innovative Healing Methods
(Evgenia Paxinou, George Lagoumintzis, Zoi Zagoriti, Athanasios Niarchos, Ilias Boltsis, Konstantinos Poulas, Department of Pharmacy, University of Patras, Greece)

Chapter 2
Hard­-to­-Heal Venous Leg Ulcers: Prognostic Factors and Therapeutic Strategies
(Marian Simka, College of Applied Sciences, Department of Nursing, Ruda Slaska, Poland)

Chapter 3
Drugs that Interfere in the Healing Process of Leg Ulcers
(Norma Gondim Cléto, Paula Yoshiko Masuda, Patrick Alexander Wachholz, Dejair Caitano do Nascimento, Dermatology department
Instituto Lauro de Souza Lima, Bauru - Sao Paulo- Brazil, and others)

Chapter 4
Papain-Based Gel for the Treatment of Leg Ulcers
(Beatriz Guitton Renaud Baptista de Oliveira, Andrea Pinto Leite Ribeiro, Débora Omena Futuro, Head Professor of the Department of Nursing Fundamentals and Administration at Aurora de Afonso Costa School of Nursing (EEAAC) - Fluminense Federal University (UFF). Brazil, and others)

Chapter 5
Ultrasound as Therapy for Leg Ulcer Treatment
(Luísiane of Avila Santana, Professor course of Physiotherapy, Faculty of Ceilândia , University of Brasilia (UNB-FCE), Brasilia, Distrito Federal, Brazil)

Chapter 6
Compression Therapy for Varicose Ulcers by using the Unna Boot and Elastic Bandages
(Beatriz Guitton R. B de Oliveira, Alcione Matos de Abreu, Head Professor of the Department of Nursing Fundamentals and Administration at Aurora de Afonso Costa School of Nursing (EEAAC) - Fluminense Federal University (UFF). Brazil, and others)

Chapter 7
Antiseptics used in the Therapeutic Management of the Leg Chronic Wounds
(Mihaela Georgescu, Luminiþa Dascãlu, Viorel Trifu, Viorica Marinescu, Ionel Þoropoc, Doru Aurel Chiriþã, Marcela Poenaru, Monica Sorina Dãrmãnescu, Daniel Costache, Mariana Carmen Chifiriuc, Dr. Carol Davila Central Military Universitary Emergency Hospital “SUUMC Dr. Carol Davila”, Romania, and others)

Chapter 8
Platelet-Rich Plasma (Prp) in Treating Chronic Wounds, A Current View
(Andre Mancilha Cancela, Stephany Cares Huber, Rebeca Bonani Brito Cancela, José Fabio Santos Duarte Lana, Aline Urban Paffaro, Joyce Maria Annichino-Bizzacchi, Vascular Surgeon. Regenerative and Cell Therapy Group. Hemocentro. University of Campinas. Campinas, SP, Brazil, and others)

Chapter 9
Modulating the Foreign Body Response to Treat Chronic Wounds
(Melanie R. Major, Emily R. Nelson, Victor W. Wong, Department of Plastic and Reconstructive Surgery, Johns Hopkins School of Medicine, USA)


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