Lecithins and Phospholipids: Biochemistry, Properties and Clinical Significance


Jason Hernandez (Editor)

Series: Biochemistry Research Trends
BISAC: SCI007000

Phospholipids are the main components of biological membranes. This book covers the production, properties and use of natural and synthetic phospholipids as drug delivery systems for therapeutic agents, including small drugs, peptides/proteins and nucleic acids. Also covered in this book are major recent findings that elucidate the biochemical features of polyphenol-phospholipid interactions and their influence on the mechanical and biochemical properties of membranes; research on the metabolism of phospholipids and their fatty acids content, fragmentally altered in various diseases; information dealing with the various aspects of different metallodrugs with phospholipids and their analysis in the light of their importance in cancer therapy; the synthesis and metabolism of major membrane phospholipids; and an in-depth discussion on the synthesis of other phopholipids, including lecithin are examined as well.
(Imprint: Nova)


Table of Contents

Table of Contents


Chapter 1
Physiological Roles and Possible Applications of Lecithin
(Tzi Bun Ng and Charlene Cheuk Wing Ng, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, Hong Kong, China)

Chapter 2
Phospholipid-Based Drug Delivery Systems: Scopes and Limitations
(Isabel Ribeiro1 and Célia Faustino, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, Lisbon, Portugal)

Chapter 3
Phospholipids and Metallodrugs: Is their Interaction Essential for Cancer Therapy?
(Marijana Petković, Jovana Bogojevski, Maja Nešić, Biljana Petrović, Iva Popović and Živadin Bugarčić, Department of Physical Chemistry, ―Vinča― Institute of Nuclear Sciences, University of Belgrade, Belgrade, Serbia, and others)

Chapter 4
Phospholipids Fatty Acid Profile as Biomarker of Dietary Intake and Indicator of Chronic Diseases
(Aleksandra Arsic and Danijela Ristic-Medic, Centre of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, University of Belgrade, Belgrade, Serbia)

Chapter 5
Role of Membrane Phospholipids in Cardiovascular Diseases
(Poulami Basu and Marica Bakovic, Department of Human Health and Nutritional Science, University of Guelph, Guelph, Ontario, Canada)

Chapter 6
Interactions of Natural Polyphenols with Phospholipids: Implication in Oxidative Stress and Neurodegenerative Diseases
(Ekaterina A. Korobkova, John Jay College of Criminal Justice at the City University of New York, New York, NY, USA)



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