Laryngeal Cancer: Risk Factors, Symptoms and Treatment

Andrea De Vito, M.D., Ph.D. (Editor)
Head and Neck Department, ENT Unit and Oral Surgery, Morgagni-Pierantoni Hospital, AUSL of Romagna, Forlì, Italy

Sheng-Po Hao, M.D. (Editor)
Department of Otolaryngology Head and Neck Surgery, Comprehensive Oral Cancer Center, Shin Kong Wu Ho-Su Memorial Hospital, Taiwan

Claudio Vicini, M.D. (Editor)
Head and Neck Department, ENT Unit and Oral Surgery, Morgagni-Pierantoni Hospital, AUSL of Romagna, Forlì Italy

Series: Cancer Etiology, Diagnosis and Treatments
BISAC: MED062000

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Laryngeal cancer is one of the most common cancers of the head and neck. The best diagnostic approach is provided by performing a full endoscopic evaluation, appropriate imaging and biopsy. Therapy can thereafter be tailored to pathology, stage of disease, and then individualized.

The multidisciplinary tumor board represents an essential requirement in oncologic diagnosis and treatment, often introducing clinical challenges which force us to overcome our personal opinion in solving a case in a specific manner.

This book represents a collection of our retrospective analysis of the local weekly tumor board which includes the otorhinolaryngologist, oncologist, radiotherapist, pathologist, radiologist and speech pathologist. We have also included reviews from national and international opinion leaders in the field of laryngeal cancer.

The book is organized into three sections: basic science, diagnostic work-up and treatment, with the aim of providing a concise, up-to-date, and appropriate overview of the anatomy, risk factors, conventional and newest diagnostic management, open partial laryngectomies, laser CO2 transoral laryngeal microsurgery, and conventional and robotic total laryngectomy.

The authors hope to procure a practical guideline for medical students, general practitioners, ENT specialists and, moreover, medical specialists whose roles are to provide the best up-to-date diagnostic and therapeutic management to patients with laryngeal cancer.

Preface

Chapter 1. Anatomy and Embryology of the Larynx
(Chiara Bellini, Riccardo Gobbi, Soon Sue Rene, and Andrea De Vito, Head&Neck Department, ENT Unit and Oral Surgery, Morgagni-Pierantoni Hospital, AUSL of Romagna, Forlì, Italy, and others)

Chapter 2. Risk Factors in Laryngeal Cancer
(Marco Mandalà, Giulia Coralli, Leopoldo Brindisi, Sabrina Frassineti, and Andrea De Vito, Ear and Skull Base Surgery Unit, AOUS, Siena, Italy, and others)

Chapter 3. Classification of Laryngeal Malignant Tumors and Staging
(Giuseppe Meccariello, Giovanni Cammaroto, Marchi Chiara, and Matteo Costantini, Head&Neck Department, ENT Unit and Oral Surgery, Morgagni-Pierantoni Hospital, AUSL of Romagna, Forlì, Italy, anothers)

Chapter 4. Signs and Symptoms -
(Giovanni D’Agostino, Soon Sue Rene, Elisabetta Firinu, and Piercarlo Frasconi, Head&Neck Department, ENT Unit and Oral Surgery, Morgagni-Pierantoni Hospital, AUSL of Romagna, Forlì, Italy)

Chapter 5. Diagnostic Imaging for Larynx
(Elena Amadori, Domenico Barone, Andrea, Moretti, Andrea Galassi, and Federica Matteucci, Radiology Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, and others)

Chapter 6. Diagnostic Management of Laryngeal Cancer
(Andrea De Vito, Soon Sue Rene, Andrea Lorenzetti, Stefano Savini, and Claudio Vicini, Head&Neck Department, ENT Unit and Oral Surgery, Morgagni-Pierantoni Hospital, AUSL of Romagna, Forlì, Italy, and others)

Chapter 7. Transoral Laser Microsurgery
(Filippo Carta, Giovanni D’Agostino, Soon Sue Rene, Andrea De Vito, and Roberto Puxeddu, Department of Surgery & Stomatology Science, ENT Clinic, S. Giovanni di Dio Hospital, Cagliari Italy, and others)
Chapter 8. Conservation Surgery: Open Partial Laryngectomy
(Alfredo Quintin Y. Pontejos Jr., Daryl Anne A. del Mundo, Soon Sue Rene, Andrea De Vito, and
Sheng-Po Hao, Department of Otorhinolaryngology, University of the Philippines, Philippine General Hospital, Manila, Philippines, and others)

Chapter 9. Surgical Management of Advanced Laryngeal Tumors
(Andrea De Vito, Soon Sue Rene, Patrizia Bezzi, Francesco Soprani, Pierre El-Chater, and Darius Abedipour, Head&Neck Department, ENT Unit and Oral Surgery, Morgagni-Pierantoni Hospital, AUSL of Romagna, Forlì, Italy, and others)

Chapter 10. Transoral Robotic Laryngectomy
(Filippo Montevecchi, Claudio Vicini, Mohamed S. Rashwan, Hayfa Obaidat, and Sandeep Dachuri, Head&Neck Department, ENT Unit and Oral Surgery, Morgagni-Pierantoni Hospital, AUSL of Romagna, Forlì, Italy)

Chapter 11. Neck Dissection in Laryngeal Cancer
(Giuseppe Meccariello, Andrea De Vito, Giovanni Cammaroto, Stefano Savini, and Claudio Vicini, Head&Neck Department, ENT Unit and Oral Surgery, Morgagni-Pierantoni Hospital, AUSL of Romagna, Forlì, Italy, and others)

Chapter 12. Conservative Therapy: Radiotherapy and Chemotherapy for Laryngeal Cancer
(Elisabetta Parisi and Sebastiano Calpona, Radiotherapy Department, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, and others)

Index

“Professors De Vito, Hao, and Vicini have assembled an impressive group of experts and achieved their goal of delivering a concise and contemporary overview of the relevant anatomy, risk factors, diagnostic evaluation, surgical management, and organ preservation therapies for laryngeal cancer. This book serves as an excellent resource for both trainees and practitioners interested in laryngeal cancer.” - David W. Eisele, MD, FACS, Andelot Professor and Director, Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

Keywords: LARYNGEAL CANCER, TRANS-ORAL MICROSURGERY, CORDECTOMY, TOTAL LARYNGECTOMY, PARTIAL LARYNGECTOMY, NARROW BAND IMAGING, RADIOCHEMOTHERAPY, TRANS-ORAL ROBOTIC SURGERY

Audience: general, practioner, oncoloyst, radiotherapist, nuclear medicine doctors, radiologist, otorhinolaryngologist in training

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