Ketamine: History, Uses and Health Effects


Leland A. McBride (Editor)

Series: Pharmacology – Research, Safety Testing and Regulation
BISAC: MED071000

Ketamine: History, Uses and Health Effects first compares the pathology of the urinary system in ketamin- treated mice with those treated by Uncaria rhynchophylla plus e and Gouteng-treated mice.

This compilation goes on to assess the current literature regarding the effectiveness and the adverse effects of ketamine in burn pain management, coming to conclusions about its potential clinical use for burns among children and adults.

Following this, the authors provide cellular, and molecular evidence regarding the ketamine effects in clinical and preclinical models of major depressive disorder.

A critical review on ketamine and other phencyclidine analogues, namely the most consumed metoxethamine, 3-methoxyphencyclidine and 4-methoxyphencyclidine, is also provided.

Lastly, a new approach for the on-site detection and quantification of ketamine based on the isolation of its product of reaction with gold bromide onto nylon filters and subsequent digital color analysis is presented.
(Imprint: Nova Medicine and Health)

Table of Contents

Table of Contents


Chapter 1. Can Uncaria Rhynchophylla Protect the Urinary System of Mice from Pathological Damage by Ketamine but Raise Creatinine Level in Long Term Treatment?
(Tony C. H. Chow, Gigi C.T. Leung, Regina S. Y. Cheng, K. S. Wong and David T. Yew)

Chapter 2. Ketamine in Burn Pain Management: A Review
(Areti Katsouda, MD, and Maria Mironidou-Tzouveleki, MD, PhD, Laboratory of Pharmacology, Medical School, Aristotle University of Thessaloniki, Greece)

Chapter 3. Ketamine, Fast-Acting Antidepressant and Synaptic Effects: An Overview
(Andiara E. Freitas and Isabella A. Heinrich, Neurobiology Section, Biological Sciences Division, University of California, San Diego, CA, US, and others)

Chapter 4. Ketamine and Other Phencyclidine Analogues: A Review of Their Use as Drugs of Abuse, Toxicological Aspects and Bioanalytical Approaches
(Ana Sofia Vargas, Débora Caramelo, Ana Y. Simão, Sofia Soares, Joana Gonçalves, Tiago Rosado, Mónica Antunes, Mário Barroso, PhD, and Eugenia Gallardo, PhD, Centro de Investigação em Ciências da Saúde, Universidade da Beira Interior, Covilhã, Portugal, and others)

Chapter 5. On-Site Detection and Quantification of Ketamine in Illicit Samples by Digital Color Analysis
(R. Herráez-Hernández, N. Jornet-Martínez, N. Fernández-Ortiz and P. Campíns-Falcó, Department of Analytical Chemistry, University of Valencia, Valencia, Spain)


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