Isoprenoids: Polyprenols and Polyprenyl Phosphates as Physiologically Important Metabolic Regulators


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Series: Chemistry Research and Applications
BISAC: SCI013040

This book defines and classifies polyisoprenoids, describes the characteristics of polyprenols, dolichols and their phosphates, and the metabolism of polyprenols and their derivatives, discusses the biological role of polyprenols, and analyzes the function of polyprenols in the regulation of cholesterol synthesis and the role of phytosterols in the suppression of cholesterol absorption in the gastrointestinal tract.

It also describes the hepatoprotective and anti-inflammatory effect of polyprenols and separately discusses the current understanding of the mechanisms of dyslipidemia and metabolic syndrome development. This review contains background information on the newly developed drugs based on polyprenols and polyprenyl phosphates, which are highly promising in veterinary and human medicine.

Table of Contents

Table of Contents


Chapter 1. Polyisoprenoids and the Isoprenoid System: Definition and Classification

Chapter 2. Metabolism of Polyprenols and Their Derivatives

Chapter 3. Biological Role of Polyprenols and Dolichol

Chapter 4. General Principles of Preparation of Phosphopolyprenols and Their Glycosyl Esters

Chapter 5. Approaches to the Search for Antibacterial Drugs Based on Polyprenols

Chapter 6. Polyprenols and Their Derivatives as Potential Objects for Molecular Medicine

Chapter 7. Approaches to the Prevention and Treatment of Atherosclerosis with Polyprenols

Chapter 8. Metabolic Syndrome and Polyprenyl Phosphates

Chapter 9. Experimental Investigation of Specific and General Pharmacological Activity of Sodium Polyprenyl Phosphate (PPPhNa)

Chapter 10. Experience in the Use of Polyprenyl Phosphates in Veterinary Medicine

Chapter 11. Polyisoprenoid-Based Drugs



Additional Information

Keywords: polyisoprenoids, polyprenols, dolichols and their phosphates, metabolism of polyprenols and their derivatives, antiviral, hepatoprotective and anti-inflammatory effect of polyprenols, dyslipidemia, and metabolic syndrome

It is of great interest to a wide range of readers, including chemists, biologists, pharmacologists and physicians.

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