Interstitial Lung Disease: From Diagnosis to Treatment

$310.00

Roberto G. Carbone, MD, FCCP – Professor, Consultant, Department of Internal Medicine, University of Genoa, Italy
Francesco Puppo, MD – Full Professor, Department of Internal Medicine, University of Genoa, Italy
Keith Wille, MD, MSPH  – Professor of Medicine, University of Birmingham, AL, USA
Pallav Shah, MD – Professor of Medicine, National Heart & Lung Institute, Imperial College, London, UK

Series: Pulmonary and Respiratory Diseases and Disorders
BISAC: MED079000
DOI: https://doi.org/10.52305/XGNW5068

This book highlights recent advances in the understanding of interstitial lung disease (ILD) from diagnosis to treatment. The first part of the book discusses general aspects of ILD, such as genetics, epidemiology, classification, pathophysiology, pathology, imaging, and clinical approach including management of ILD comorbidities such as gastroesophageal reflux and pulmonary hypertension. The second part describes common ILDs like idiopathic interstitial pneumonias, sarcoidosis, and hypersensitivity pneumonitis as well as ILDs associated with connective tissue diseases or induced by exposure to environmental agents, drugs, and radiation. Lastly, the third part of the book is devoted to rare ILDs including eosinophilic lung disease and reports on current therapy guidelines.

Table of Contents

Preface

Chapter 1. An Overview of Classification, Epidemiology and Pathophysiology of Interstitial Lung Disease
Keith C. Meyer, MD
Lung Transplant and Advanced Pulmonary Disease Program Section of Allergy, Pulmonary and Critical Care Medicine Department of Medicine
University of Wisconsin School of Medicine and Public Health Clinical Science Center, Madison, WI, USA

Chapter 2. New Advances in Genetic Predisposition
Anna L. Peljto1, DrPH and Tasha E. Fingerlin1,2, PhD
1University of Colorado School of Medicine, Aurora, CO, USA
2 Center for Genes, Environment & Health, National Jewish Health, Denver, CO, USA

Chapter 3. Mechanisms of Lung Fibrosis
Loka Raghu Kumar Penke, MD and Steven K. Huang, MD
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine,
University of Michigan Medical School, Ann Arbor, MI, USA

Chapter 4. Extracellular Matrix Proteins as Biomarkers of Acute Exacerbation of Idiopathic Interstitial Pneumonia
Yuki Sato, MD, PhD, Yoshinori Tanino, MD, PhD, Takefumi Nikaido, MD, PhD, Ryuichi Togawa, MD, Takaya Kawamata, MD, Natsumi Watanabe, MD, Xintao Wang, MD, PhD, and Yoko Shibata, MD, PhD
Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan

Chapter 5. Immunopathogenesis of Pulmonary fibrosis
Kazuya Tsubouchi, Takuma Isshiki, Kjetil Ask and Martin R. J. Kolb
Firestone Institute for Respiratory Health, Research Institute at St. Joseph’s Healthcare, Department of Medicine, McMaster University, Hamilton, ON, Canada

Chapter 6. Gastro-Esophageal Reflux
Vincenzo Savarino1, MD, and Edoardo Savarino2, MD
1Department of Internal Medicine and Medical Specialties, University of Genoa, Genoa, Italy
2Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy

Chapter 7. Microbiome and Interstitial Lung Disease
Roberto G. Carbone, MD and Francesco Puppo, MD
Department of Internal Medicine, University of Genoa, Genoa, Italy

Chapter 8. A Clinical Approach to Interstitial Lung Disease Diagnosis
Roberto G. Carbone1, MD, Francesca Conway2 and Pallav L. Shah2, MD
1Department of Internal Medicine, Uhniversity of Genoa, Genoa, Italy
2National Heart and Lung Institute, Imperial College London, London, UK

Chapter 9. Pathology of Diffuse Parenchymal Lung Disease
Anja C. Roden1 and Yasmeen M. Butt2
1
Department of Laboratory Medicine and Pathology, Mayo Clinic Rochester, MN
2Department of Laboratory Medicine and Pathology, Mayo Clinic Scottsdale, AZ, USA

Chapter 10. Pulmonary Hypertension in Interstitial Lung Diseases
Tasnim Lat1, MD, Peter Yau1, MD, Adriel Malave2, MD, Reda E. Girgis3, MD, and Deborah J. Levine2, MD
1Division of Pulmonary, Critical Care & Sleep Medicine Baylor Scott & White Health – Temple Memorial, Temple, TX, USA
2Division of Pulmonary, Critical Care & Sleep Medicine, University of Texas at San Antonio Health Sciences Center, San Antonio, TX, USA
3Division of Pulmonary, Critical Care & Sleep Medicine Michigan State University, Grand Rapids, MI, USA

Chapter 11. Clinical Value of Cardiopulmonary Exercise Testing in Interstitial Lung Diseases
Thomas Gille1,2, MD, Raphaëlle Ohayon3,4, MD, and Pierantonio Laveneziana3,4, MD
1Université Sorbonne Paris Nord (USPN), INSERM, UMR 1272 Hypoxia & the Lung, UFR SMBH Léonard de Vinci, Bobigny, France
2Assistance Publique – Hôpitaux de Paris (AP-HP), Groupe Hospitalo-Universitaire Paris-Seine-Saint-Denis (GHUPSSD), Hôpital Avicenne, Service de Physiologie et Explorations Fonctionnelles du Département Médico-Universitaire NARVAL, Bobigny, France
3Sorbonne Université, INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France
4Assistance Publique – Hôpitaux de Paris (AP-HP), Groupe Hospitalier Universitaire APHP-Sorbonne Université, sites Pitié-Salpêtrière, Saint-Antoine et Tenon, Service des Explorations Fonctionnelles de la Respiration, de l’Exercice et de la Dyspnée (Département R3S), Paris, France

Chapter 12. Idiopathic Pulmonary Fibrosis: State of the Art Research
Tanzira Zaman, MD; Giuliana Cerro Chiang, MD and Paul W. Noble, MD
Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA

Chapter 13. Non-IPF Idiopathic Interstitial Pneumonias
Zhe Wu, MD, Philip L. Molyneaux, MD, and Felix Chua, MD
National Lung and Heart Institute Imperial College London and Royal Brompton Hospital, London, UK

Chapter 14. Sarcoidosis
Anneka Hutton, MD and Joseph Barney, MD
University of Alabama, Birmingham (AL), USA

Chapter 15. Hypersensitivity Pneumonitis
David A. Dorward, MBChB, PhD, Mark R. Jones, MBChB, and Nik Hirani, BMBS, PhD
University of Edinburgh & Edinburgh Royal Infirmary, Edinburgh, UK

Chapter 16. Connective Tissue Disease and Vasculitis
Francesco Puppo, MD, Roberto G. Carbone, MD, and Simone Negrini, PhD
Department of Internal Medicine, University of Genoa, Genoa, Italy

Chapter 17. ILD and Occupational and Environmental Exposure
Jean Paul Higuero Sevilla1, MD, Lisa A. Maier2, MD, MSPH, FCCP and Mridu Gulati1,*, MD MPH
1Yale Section of Pulmonary, Critical Care and Sleep Medicine, Occupational and Environmental Medicine Program, Yale School of Medicine, New Haven, CT, USA
2Division of Environmental and Occupational Health Sciences, National Jewish Health, Denver, CO, USA

Chapter 18. Interstitial Disease Induced by Drugs and Radiation
Mashiyat Mayisha Ahmad1, Tanweer Kurmoo1, Saira Nawaz1, Dalia Mudawi2, MBBS and Nazia Chaudhuri3, MD, PhD
1Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK
2 Manchester University NHS Foundation Trust, Manchester, UK
3 Manchester University NHS Foundation Trust, University of Manchester, Manchester, UK

Chapter 19. Eosinophilic Interstitial Lung Disease
Traci N. Adams and Jonathan C Weissler
Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine and Division of Hospital Medicine. University of Texas Southwestern Medical Center, Dallas, Texas, USA

Chapter 20. Respiratory Tract Amyloidosis
Jahanzaib Khwaja1, Ricky Thakrar2 and Ashutosh D Wechalekar1,3
1Department of Haematology, University College London Hospitals, London, UK
2 Department of Respiratory Medicine, University College London Hospitals, London, UK
3 National Amyloidosis Centre, University College London, London, UK

Chapter 21. Rare and Orphan Interstitial Lung Diseases
Anila N. Khan, MD, and Daniel F. Dilling, MD
Loyola University Chicago, Stritch School of Medicine, Division of Pulmonary and Critical Care, IL, USA

Chapter 22. Graft Versus Host Disease
Meenakshi Sridhar 1 MD; Mallory P. Portz 2 DNP, RN and Keith M. Wille 1, MD, MSPH
Department of Medicine1, Department of Nursing2, University of Alabama at Birmingham, Birmingham, AL, USA

Chapter 23. Interstitial Lung Disease in Cardiac Surgery
Roberto G. Carbone1, MD, Assaf Monselise2, MD, and Giovanni Bottino1, MD
1Department of Internal Medicine, University of Genoa, Genoa, Italy
2Clalit Health Services, Tel Aviv, Israel

Chapter 24. SARS-COV-2 Infection: Acute Respiratory Distress Syndrome and Post-COVID Interstitial Lung Disease
Keith C. Meyer, MD
Department of Medicine University of Wisconsin School of Medicine and Public Health, Madison, WI, USA

Chapter 25. Treatment of an Interstitial Lung Disease
Abhinav K. Misra and James R. Klinger
Division of Pulmonary, Sleep, and Critical Care Medicine, Rhode Island Hospital, and the Alpert Medical School of Brown University, Providence, RI, USA

Chapter 26. Current Therapeutic Guidelines for Interstitial Lung Diseases
Syazatul Syakirin1, MD, MRCP, and Arata Azuma2, MD, PhD
1Respiratory Medicine, Institut Perubatan Respiratori, Ministry of Health, Malaysia
2Pulmonary Medicine and Oncology, Nippon Medical School, Tokyo, Japan

Chapter 27. Does a Lung Transplant Confer a Survival Advantage?
Alicia B Mitchell1 and Allan R Glanville2
1
Sydney Medical School, University of Sydney, Sydney, NSW, Australia
2The Lung Transplant Unit, St. Vincent’s Hospital, Sydney, NSW, Australia

Index


Editor’s ORCID iD

Roberto G. Carbone 0000-0002-6633-9707