Inositol: Synthesis, Functions and Clinical Implications

Henrique Rocha (Editor)
Marina Cardoso (Editor)

Series: Biochemistry Research Trends
BISAC: SCI007000

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Volume 10

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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In this book, the authors present topical research in the study of the synthesis, functions and clinical implications of inositol. Topics discussed include hypoxia and angiogenesis related myo-inositol phosphates; inositol derivatives in mycobacterium tuberculosis; inositols and epilepsy; the contribution of inositol trisphosphate signaling to cardiac pathologies; the role of inositol 1,4,5-triphosphate receptor in hepatorenal syndrome; the pathophysiologic significance of inositol phosphates (IP) in Alzheimer’s and bipolar disorder; design and synthesis of biotinylated inositol phosphates; the health benefits of inositol and inositol hexaphosphate; and the cellular functions of inositol. (Imprint: Nova Biomedical )

Preface

Hypoxia- and Angiogenesis-Related myo-Inositol Phosphates: Synthesis and Biological Evaluation
(Alexandros E. Koumbis, Konstantina C. Fylaktakidou, Laboratory of Organic Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece, and others)

Inositol Derivatives in Mycobacterium Tuberculosis: Function, Biosynthesis and Therapeutic Implications
(Xinyi Huang, Marcy Hernick, Department of Biochemistry, Virginia Tech, Blacksburg, VA, USA)

Inositols and Epilepsy
(R. Solomonia, E. Lepsveridze, T. Kiguradze, M. Nozadze, Institute of Chemical Biology, Ilia State University, Tbilisi, Republic of Georgia, and others)

The Contribution of Inositol Trisphosphate Signaling to Cardiac Pathologies
(Elizabeth A. Woodcock, Molecular Cardiology Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia)

The Role of Inositol 1,4,5-Triphosphate Receptor in Hepatorenal Syndrome
(Dong-Lei Wang, Pei Liu, Department of Infectious Diseases, The First Affiliated Hospital, China Medical University, Shenyang City, Liaoning Province, P.R. China)

Pathophysiologic Significance of Inositol Phosphates (IPs) in Alzheimer’s Disease
(Krishnaswamy Kannan, Rakhee Agarwal, Nawab Ali, Department of Applied Science, University of Arkansas at Little Rock (UALR), Little Rock, AR, USA, and others)

Design and Synthesis of Biotinylated Inositol Phosphates: Application to the Inositol Phosphate-Protein Binding Analysis
(Kensaku Anraku, Mikako Fujita, Takashi Morii, Yasuo Mori, Yoshinari Okamoto, Masami Otsuka, Institute of Health Sciences, Kumamoto Health Science University, Izumi-machi, Kita-ku, Kumamoto, Japan, and others)
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Health Benefits of Inositol and Inositol Hexaphosphate
(Tzi Bun Ng, Charlene Cheuk Wing Ng, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, Hong Kong, China)

Cellular Functions of Inositol
(Tzi Bun Ng, Charlene Cheuk Wing Ng, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, Hong Kong, China)

Index

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