Inflammasomes: Mechanism of Action, Regulation and Role in Disease

Angie Mason (Editor)

Series: Biotechnology in Agriculture, Industry and Medicine
BISAC: SCI010000

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The term inflammasome was coined over a decade ago to describe the molecular platform activated by pathogens or stressor molecules where inflammatory caspases are triggered and cleavage of IL-1â takes place. Inflammasome regulation is critical for the maintenance of homeostasis: an imbalance in this fine-tuning is responsible for the establishment of infectious, autoimmune, metabolic and neurodegenerative diseases. This book examines the activation and function of inflammasomes during fungal infections; inflammasome involvement in carcinogenesis; and the role of inflammasomes in protozoan infections. (Imprint: Novinka)

Preface

Chapter 1. Activation and Function of Inflammasomes during Fungal Infections
Guangxun Meng and Mingkuan Chen (Unit of Innate Immunity, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China)

Chapter 2. Inflammasomes in Tumorigenesis: Implications in Bladder Cancer
Giulia Poli, Giovanni Cochetti, Stefano Brancorsini, Maria Giulia Egidi and Ettore Mearini (Department of Experimental Medicine-Section of Terni, University of Perugia, Italy, and others)

Chapter 3. The Emerging Role of Inflammasomes in Protozoan Infections
Jeanie Quach and Kris Chadee (University of Calgary, Cumming School of Medicine, Snyder Institute for Chronic Diseases, 3330 Hospital Drive NW, Calgary, Alberta, Canada)

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