Immune Modulation by Probiotics: State of the Art

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Alessandro Di Cerbo, PhD
Department of Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena, Italy

Beniamino Palmieri, MD, PhD
Department of Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena, Italy

Maria Aponte
Department of Agriculture, University of Naples “Federico II”, Portici (NA), Italy

Series: Microbiology Research Advances
BISAC: MED008000

The authors reviewed a wide number of microbiological and medical papers outlining the profile of different probiotic strains in the immune-modulating activity related to major and minor clinical impairment of soluble and cell-mediated immunity. Starting from in vitro and experimental animal studies, a good number of clinical trials are reported, enclosing an update of the side effects of the probiotic long-term administration.

Conclusively, the biological therapies are currently oriented to direct delivery of cytokines and molecules involved in the immune process enhancement. Using probiotics to sustain the immune response and to rescue the suppressed immunity is still a very modern approach, being also cheap and practical. This review highlights the rationale for this probiotic therapeutic indication which is largely safe and reliable. (Imprint: Nova Biomedical )

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Table of Contents

Abstract

Acknowledgments

Chapter 1 – Introduction (pp. 1-2)

Chapter 2 – Chronology of Probiotics Modulated Immunity Studies (pp. 3-30)

Chapter 3 – The New Era of Probiotics (pp. 31-126)

Chapter 4 – Interesting Perspectives and Insights on Probiotics (pp. 127-156)

Chapter 5 – Conclusion (pp. 157-160)

Chapter 6 – References (pp. 161-184)

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