IgG4 Related Disease: Illustrated Pathology of Novel Systemic Disease

Syuichi Koarada, MD (Editor)
The Division of Rheumatology Saga University, Japan

Series: Immunology and Immune System Disorders
BISAC: MED044000

IgG4-related disease (IgG4-RD) is an increasingly recognized and novel systemic inflammatory disorder characterized by tumefactive lesions with infiltrating IgG4-positive plasma cells. The disease affects virtually every organ system. Immunologically, plasmablasts increase in patients with IgG4-RD in which activation and dysregulation of B cells may be involved. Accurate characterization by a method using various modalities and immunological evaluation including plain radiography, ultrasound, CT, scintigraphy, MRI and flow cytometry should be required. Comprehensively, we review and illustrate the systemic and organ-specific findings of IgG4-RD.

This book shows a systematic and organ-specific evaluation of immunological and radiological findings for general practitioners. Moreover, the book is also interesting for the subspecialists including rheumatologists, dermatologists, otologists, respiratory physicians, clinical immunologists and radiologists, and patients and their families because patients with IgG4-RD visits every subspecialist by the tremendous various clinical symptoms and findings.

The study in the book included 147 patients with IgG4-RD who visited Saga University Hospital from January 1, 2001 to March 31, 2020. Although the number of patients studied in this monograph was not so large, the patients evaluated and treated by a single institution are considered clinically valuable. (Imprint: Nova Medicine and Health)

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Volume 10

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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Table of Contents

Preface

Acknowledgements

Chapter 1. Introduction of IgG4-Related Disease
(Syuichi Koarada, Nobuyuki Ono and Yoshifumi Tada, Division of Rheumatology, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan)

Chapter 2. IgG4-Related Disease in Head and Neck
(Syuichi Koarada and Mariko Sakai, Division of Rheumatology, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan)

Chapter 3. IgG4-Related Disease in Urinary Tract, IgG4-Related Retroperitoneal Fibrosis and Related Disorders
(Syuichi Koarada and Yoshinobu Nakao, Division of Rheumatology, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan)

Chapter 4. IgG4-Related Disease in Urinary Tract, IgG4-Related Retroperitoneal Fibrosis and Related Disorders
(Syuichi Koarada and Yukiko Takeyama, Division of Rheumatology, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan)

Chapter 5. Cardiovascular Manifestations of IgG4-Related Disease
(Syuichi Koarada and Yuri Shirahama, Division of Rheumatology, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan)

Chapter 6. Musculoskeletal Manifestations of IgG4-Related Disease
(Syuichi Koarada and Satoko Tashiro, Division of Rheumatology, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan)

Chapter 7. Abdominal Manifestations of IgG4-Related Disease
(Syuichi Koarada and Akihito Maruyama, Division of Rheumatology, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan)

Chapter 8. Other Involved Organs and Tissues, Candidate Members of IgG4-RD and Uncommon Manifestations of Each IgG4-RD
(Syuichi Koarada and Mariko Sakai, Division of Rheumatology, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan)

Chapter 9. Overview of IgG4-Related Diseases by Pictorial Clinical Immunology
(Syuichi Koarada and Yoshinobu Nakao, Division of Rheumatology, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan)

Index

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