Hypericum: Botanical Sources, Medical Properties and Health Effects


Howard R. Davis (Editor)

Series: Plant Science Research and Practices
BISAC: NAT026000

The genus Hypericum is the most important of the Hypericaceae family, widespread all over the world, with about 400 species. It is a herbaceous perennial plant native to Europe and Asia. The authors focus on Hypericum perforatum L, one of the most well-known species, which is widely diffused in dry meadows, in forest clearances, along tracks and roads, from the sea level up to 1600 m of elevation. Also known as St. John’s wort, the applications of Hypericum perforatum L are reviewed.

Literature data on ethnobotanical practices, main active constituents, pharmacological activity and applications of Hypericum species throughout the world are discussed as well. Other chapters review cadmium (Cd) and lead (Pb) concentration in the herbs of Hypericum species; hyperforin as the main active component of the Hypericum perforatum extract and its medicinal uses; and finally, Hypericum sinaicumis is discussed, one of the rarest species. In particular, the distribution of species is addressed and the environmental factors affecting it.
(Imprint: Nova)


Table of Contents

Table of Contents


The Secreting Structures of the Genus Hypericum, with Particular Reference to Hypericum perforatum L.
(Laura Maleci Bini, Claudia Giuliani, Department of Biology, University of Florence, Italy)

Potential of the Balkan Flora as a Source of Prospective Hypericum Genotypes for the Conventional and Biotechnological Delivery of Phytopharmaceuticals
(Kalina Danova, Institute of Organic Chemistry with centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia, Bulgaria)

St. John’s Wort (Hypericum spp.) – Relation between the Biological Source and Medical Properties
(Nebojša Kladar, Branislava Srđenović, Nevena Grujić, Milica Rat, Neda Gavarić, Goran Anačkov, Biljana Božin, Department of Pharmacy, Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia, and others)

A Commercially Available Product of Hypericum Perforatum Acts on GABAA Receptor to Produce Anxiolytic-Like, but not Antidepressant-Like Effects in Wistar Rats
(Juan Francisco Rodríguez-Landa, Jonathan Cueto-Escobedo, Juan de Dios Aguirre-Chiñas, and Magda Olivia Pérez-Vásquez, Instituto de Neuroetología, Universidad Veracruzana, Colonia Industrial Ánimas, Xalapa, Veracruz, México, and others)

Quality and Safety of Hyperici Herbs: Reference to the Content of Toxic Metals Cadmium and Lead
(Danijela Đukić-Ćosić, Marijana Ćurčić, Zorica Bulat, Biljana Antonijević, Vesna Matović, Department of Toxicology ”Akademik Danilo Soldatović“, University of Belgrade – Faculty of Pharmacy, Vojvode Stepe,Belgrade, Serbia)

New Discoveries on the Hyperforin Derivative, Tetrahydrohyperforin: Closer to an Alzheimer’s Disease Treatment?
(Carla Montecinos-Oliva, Cheril Tapia-Rojas, Patricia V. Burgos, and Nibaldo C. Inestrosa, Centro de Envejecimiento y Regeneración (CARE), Departamento de Biología Celular y Molecular; Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile, and others)

Hypericum Sinaicum: A Threatened Near Endemic Medicinal Plant Growing in St. Katherine Protectorate, South Sinai, Egypt
(Mohamed S. Zaghloul, Abd El-Raouf A. Moustafa, and Dina H. Al-Sharkawy, Botany Department, Suez Canal University, Ismailia, Egypt)


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