Hydrazones: Uses and Reactions

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Isabella P. Østergaard (Editor)

Series: Chemistry Research and Applications
BISAC: SCI013040

Hydrazones: Uses and Reactions discusses how the interdisciplinary uses of hydrazones as building blocks, multifunctional linkers, aggregation‐induced‐emission luminogens illuminating mitochondria in cancer cells, and their indispensable role in drug designing makes them highly significant.

In one study, a novel hydrazone compound (E)-N’-(3,4-dihydroxybenzylidene)isobutyrohydrazide (hbibH2) was obtained from the reaction of isobutyric acid hydrazide with 3,4-dihydroxybenzaldehyde. This hydrazone compound is characterized both theoretically and experimentally.

In a subsequent study, a design of the molecules carrying hydrazone or thiosemicarbazone, as well as a sterically-hindered ortho-diphenol moiety with bioactive metal ions in a single scaffold, is presented for the purpose of the efficient inhibition of a broad spectrum of bacteria and fungi.
(Imprint: Novinka)

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Table of Contents

Preface

Chapter 1. Interdisciplinary Approaches to Hydrazones
(Abdul Roouf Bhat and Fareeda Athar, Department of Chemistry, Sripratap College, Cluster University, Srinagar, India, and others)

Chapter 2. Synthesis, Crystal Structure and Dft Studies of (E)-N’-(3,4-Dihydroxybenzylidene)Isobutyrohydrazide
(Ayşin Zülfikaroğlu and Çiğdem Yüksektepe Ataol, Department of Chemistry, Faculty of Arts and Science, Amasya University, Amasya, Turkey, and others)

Chapter 3. Redox-Active Metal Complexes with Hydrazone and Thiosemicarbazone Derivatives of 4,6-Di-Tert-Butyl-2,3-Dihydroxybenzaldehyde as Novel Antimicrobials for Medicinal Uses
(Natalia V. Loginova, Tat’yana V. Koval’chuk-Rabchinckaya, Galina A. Ksendzova, Nikolai P. Osipovich, Yaroslav V. Faletrov, Kseniya A. Nabebina, Maxim Y. Gvozdev and Genrikh I. Polozov, Department of Chemistry, Belarusian State University, Minsk, Belarus, and others)

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