Mahdieh Molanouri Shamsi, PhD – Associate Professor, Department of Physical Education & Sport Sciences, Yazd University, Iran
Sadegh Amani-Shalamzari, PhD – Associate Professor, Department of Exercise Physiology, Faculty of Sport Science, Kharazmi University, Iran
Raoof Negaresh, PhD – Assistant Professor, Department of Physical Education, Farhangian University, Iran

Series: Physical Fitness, Diet and Exercise
BISAC: MED044000; HEA009000; HEA007000
DOI: https://doi.org/10.52305/DNST2638

Physical activity and exercise are more than tools for physical fitness. Rather than isolated movements, exercise is presented as a continuous and dynamic dialogue between the body and the immune system throughout the human lifespan. How Exercise Shapes Immunity: A Lifespan View from Conception to Aging provides a comprehensive examination of this vital relationship. Using a lifespan perspective, the book illustrates how physical activity influences immune health and disease resistance from the earliest stages of human development—even before birth—through older adulthood. This book takes readers on a scientific journey beginning with the effects of maternal physical activity on fetal and neonatal immune system development. It then explores age-specific effects of physical activity on the immune system in children, adolescents, and adults. The journey continues into later life, explaining how targeted exercise interventions may help counteract immunosenescence. A key feature of this work is its emphasis on linking theory to practice. The book examines the role of physical activity in preventing and managing chronic diseases and introduces personalized exercise prescriptions based on individual immunological profiles. A dedicated chapter on the interaction between nutrition and exercise completes this approach.

Accordingly, this book serves as an essential resource for researchers, physicians, healthcare professionals, students, and scholars in sport and exercise sciences, offering evidence-based strategies to enhance immune resilience and promote lifelong health.

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