Horizons in Neuroscience Research. Volume 51


Andres Costa and Eugenio Villalba (Editors)

Series: Horizons in Neuroscience Research
BISAC: MED057000

This volume consists of twelve chapters that detail the latest neuroscience research. Chapter one examines shunt fluid as a diagnostic procedure to evaluate ventriculoperitoneal shunt malfunction and infection. Chapter two investigates the effects of lycopene on neurodegenerative diseases. The purpose of chapter three is to diagnose the state of small vesicles in the paralyzed arm of the probant and try to find a way to activate them. The objective of chapter four is to compare the density and distribution of the ‘signature’ pathological lesions in the hippocampus and adjacent PHG in fourteen neurodegenerative disorders using a standardized quantitative protocol. Chapter five investigates the effects of electrical stimulation (ES) applied to the lateral cerebellar nucleus (LCN) in rats with early and fully developed pentylenetetrazol (PTZ)-kindled seizures. Chapter six provides a review on Down’s Syndrome. Chapter seven summarizes current knowledge on P2X receptor activation, focusing on the mechanisms underlying ATP binding, conformational changes in the extracellular domain, and channel gating and desensitization. Chapter eight highlights the need for balanced, ethical, and patient-centered approaches in the evolving landscape of ADHD treatment. Chapter nine hones in on historical discoveries derived and expanded from the Xenopus frogs and tadpoles as a model organism, explores the intricate processes underpinning neural circuit formation and focuses on insights gleaned from the developing tadpole visual system.

Table of Contents


Chapter 1. The Role of Shunt Fluid Examination in the Evaluation of Shunt Infection and Malfunction
Tariq Al-Saadi¹,², MD, MSc, and Adham Al-Rahbi³
¹Department of Neurosurgery, McGill University-Montreal Neurological Institute and Hospital, Montreal, Canada
²Department of Neurosurgery, Khoula Hospital, Muscat, Oman
³College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman

Chapter 2.
The Role of Lycopene in Neurodegenerative Diseases
Jülide Secerli, Onur Erdem, and Merve Bacanli
University of Health Sciences Turkey Gülhane, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara, Turkey

Chapter 3. Synaptic Vesicles in a Post-Viral Attack by HSV: Diagnosis, Recovery and Treatment of Limb Paralysis
Kristina Zubow¹, Anatoly Zubow², and Viktor Zubow¹
¹Zubow Consulting (NPO), Germany
²Group of the Telecommunication Networks Division, TU, Berlin, Germany

Chapter 4. Neurodegenerative Diseases Affecting the Temporal Lobe of the Brain: A Quantitative Comparative Study of the Hippocampus and Adjacent Regions in Fourteen Disorders
Richard A. Armstrong
Vision Sciences, Aston University, Birmingham, UK

Chapter 5. Opposite Effects of Lateral Cerebellar Nucleus Stimulation on PTZ-Kindled Seizures
Leonid Godlevsky¹, PhD, Mykhailo Pervak¹, PhD, Olesya Poshyvak², PhD, Olga Kashchenko¹, PhD, Igor Smirnov³, PhD, Halina Volokhova¹, PhD, Viktor Balykov¹, PhD, Serhii Marchenko¹, and Enes Akyuz⁴,⁵, PhD
¹Department of Physiology and Biophysics, Odesa National Medical University, Odesa, Ukraine
²Department of Pharmacology, Danilo Halytsky Lviv National Medical University, Lviv, Ukraine
³Ukrainian Research Institute of Medical Rehabilitation and Resort Therapy, Odesa, Ukraine
⁴University of Wisconsin School of Medicine and Public Health, Wisconsin, USA
⁵ Department of Biophysics, University of Health Sciences, Istanbul, Turkey

Chapter 6. A Review on Down’s Syndrome, Patho-Physiology, Evaluation, Prognosis and Remedial Measures
R. Hemalatha¹ and G. Sridevi²
¹Professor and Head, Department of Pediatric Dentistry, SRM Dental College, Bharathi Salai, Ramapuram, Chennai, India
²Professor and Head, Department of Physiology, SRM Dental College, Bharathi Salai, Ramapuram, Chennai, India

Chapter 7. Is Purinergic Signaling (P2XRs) a New Focus in Neurodegenerative Diseases
Asuman Canak, PhD
Department of Medical Services and Techniques, Vocational School of Health Services, Recep Tayyip Erdoğan University, Rize, Turkiye

Chapter 8. Impact of Generative Artificial Intelligence and Social Media on ADHD Diagnosis and Monitoring: A Comparative Analysis of Advanced and Traditional Approaches
Antonio Pesqueira¹, Anita Schildknecht², Ioana Bolog³, Andreia de Bem Machado⁴, and Sama Bolog⁵
¹ISCTE – University Institute of Lisbon, Portugal
²Memo Health GmbH – Zurich, Switzerland
³Alnylam, Zug, Switzerland
⁴Federal University of Santa Catarina, Florianópolis, Brazil
⁵University of Basel, Basel, Switzerland

Chapter 9.
Teachings from the Tadpole: Insights into Neural Circuit Formation
Kaiyuan Zheng¹,², Sirjan Chhatwal¹,², and Kara G. Pratt¹,²
¹Department of Zoology and Physiology, University of Wyoming, Laramie, Wyoming, USA
²Program in Neuroscience,University of Wyoming, Laramie, Wyoming, USA


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